检验医学与临床2026，Vol.23Issue(17)：2352-2358,7.DOI:10.3969/j.issn.1672-9455.2026.17.008
肛周脓肿患者术后金黄色葡萄球菌致创面感染严重程度的影响因素分析
Analysis of influencing factors on the severity of wound infection caused by Staphylococcus aureus in patients with perianal abscess after surgery
摘要
Abstract
Objective To investigate the influencing factors of the severity of wound infection caused by Staphylococcus aureus in patients with perianal abscess after surgery.Methods A total of 156 patients with perianal abscess admitted to the hospital from January 2022 to July 2024 were selected as the research objects.According to the severity of wound infection,the patients with perianal abscess were divided into mild group(82 cases)and severe group(74 cases).Baseline data of all patients were collected.Real-time fluorescence quantitative polymerase chain reaction was used to detect the virulence genes and drug resistance genes of Staphylococcus aureus.Multivariate Logistic regression was used to analyze the influencing factors of severe postoperative wound infection in patients with perianal abscess.Results The proportion of patients with high abscess,the proportion of patients with diabetes and the erythrocyte sedimentation rate in the severe group were higher than those in the mild group,and the differences were statistically significant(P＜0.05).A total of 156 strains of Staphylococcus aureus were detected in 156 patients with perianal abscess postoperative inci-sion infection,of which 80 strains were detected in the mild group,accounting for 51.28％,and 76 strains were detected in the severe group,accounting for 48.72％.The detection rates of virulence genes psmα and pul and drug resistance genes mecA and Tet in the severe group were higher than those in the mild group,and the differences were statistically significant(P＜0.05).Staphylococcus aureus had a high resistance rate to Ce-fazolin and Erythromycin,and was sensitive to Vancomycin and Tiraconine.Multivariate Logistic regression a-nalysis showed that high abscess,diabetes mellitus,virulence genes psmα and pvl,drug resistance genes mecA and Tet were all independent risk factors for severe wound infection in patients with perianal abscess after surgery(P＜0.05).Conclusion The degree of postoperative infection in patients with perianal abscess is re-lated to the location of abscess,diabetes,and the number of incisions.There is Staphylococcus aureus distribu-tion in the wound,and the detection rate of virulence genes and drug resistance genes is high.Clinical rational drug use can reduce postoperative infection according to the results.关键词
肛周脓肿/创面感染/金黄色葡萄球菌/毒力基因/耐药基因/危险因素Key words
perianal abscess/wound infection/Staphylococcus aureus/virulence gene/drug resist-ance gene/risk factor分类
医药卫生引用本文复制引用
李彦娜,刘育虎,李洪,孙兴伟..肛周脓肿患者术后金黄色葡萄球菌致创面感染严重程度的影响因素分析[J].检验医学与临床,2026,23(17):2352-2358,7.基金项目
陕西省重点研发计划项目(2022SF-369). （2022SF-369）
