现代畜牧兽医Issue(8)：23-28,6.DOI:10.20154/j.cnki.issn1672-9692.2026.08.005
鹅大肠杆菌与鸭疫里默氏杆菌混合感染的病原学诊断及耐药性检测
Etiological diagnosis and antimicrobial resistance testing of mixed infection with Escherichia coli and Riemerella anatipestifer in geese
摘要
Abstract
To identify the pathogen responsible for an infectious disease with high morbidity and mortality in goslings at a large-scale goose farm in Liaoning Province,liver,air sac and other tissue samples were collected from diseased goslings for bacteriological and molecular biological identification,followed by pathogenicity tests and antimicrobial susceptibility assays.The results revealed that the pathogenic bacteria causing the disease in goslings were Escherichia coli(E.coli)and Riemerella anatipestifer(RA).The morbidity rate reached 100%in mice inoculated with each of the two isolated strains.The isolated E.coli strains exhibited resistance to some β-lactams,tetracyclines and chloramphenicols,while RA was resistant to aminoglycosides yet relatively susceptible to tetracyclines and chloramphenicols.Antimicrobial resistance profiles differed between the two pathogens;ampicillin was the shared resistant drug,whereas amoxicillin,doxycycline and enrofloxacin showed consistent susceptibility against both isolates.This study confirmed that the disease outbreak in goslings at a goose farm in Yingkou City,Liaoning Province,stemmed from co-infection with E.coli and RA.Rational selection of antimicrobials based on susceptibility test results is recommended for disease prevention and treatment.关键词
鹅/大肠杆菌/鸭疫里默氏杆菌/致病性/耐药性Key words
Geese/Escherichia coli/Riemerella anatipestifer/Pathogenicity/Antimicrobial resistance分类
农业科技引用本文复制引用
苏玉铭,高诗雨,刘海月,刘英姿,张利勃,甄志刚,赵岩,董筱萍..鹅大肠杆菌与鸭疫里默氏杆菌混合感染的病原学诊断及耐药性检测[J].现代畜牧兽医,2026,(8):23-28,6.基金项目
辽宁省自然科学基金面上项目(2024-MS-194) （2024-MS-194）
辽宁省凌海市禽病防控科技特派团项目(2025JH5/10400038) （2025JH5/10400038）
