摘要
Abstract
Liver disease in pregnancy is a critical high-risk perina-tal complication,comprising pregnancy-specific liver disorders and pre-existing liver diseases complicated by gestation.Its disease spectrum spans from physiological hepatic adaptive changes to acute life-threatening con-ditions jeopardizing maternal and fetal safety,with a global incidence of approximately 3％.Clinical manifestations often overlap with normal pregnancy-related physiological responses,posing substantial challenges to early identification and standardized management.The traditional single-disease symptomatic model is hampered by delayed intervention,inadequate risk stratification,and fragmented multidisciplinary collabora-tion,frequently leading to overtreatment of mild cases and delayed man-agement of severe cases.This study aims to establish a three-tiered hierar-chical management system centered on"preventability,disease controlla-bility,and maternal-fetal risk stratification".We systematically summa-rize the disease classification,hierarchical criteria,core diagnostic-therapeutic points,and full-cycle risk management strategies.Incorporat-ing medical ethics and humanistic care,we clarify obstetricians'role posi-tioning and decision-making boundaries,aiming to provide a standard-ized,feasible,and promotable management protocol to reduce adverse maternal-fetal outcomes and balance maternal safety with fetal prognosis.关键词
妊娠期肝病/分层管理/产科决策/多学科协作/母胎安全Key words
Liver disease during pregnancy/Hierarchical management/Obstetric decision-making/Multidisciplinary collabo-ration/Maternal-fetal safety分类
医药卫生
