内蒙古农业大学学报（自然科学版）2026，Vol.47Issue(4)：34-42,9.DOI:10.16853/j.cnki.1009-3575.2026.04.005
LEA蛋白家族及其作用机制研究进展
Research Progress on the LEA Protein Family and Its Action Mechanism
摘要
Abstract
Plants often encounter abiotic stresses during growth and development.LEA(Late Embryogenesis Abundant)proteins,as key factors in plant responses to dehydration stress,have become a research hotspot in terms of their evolution,function,and regulatory mechanisms.This article systematically reviewed the research progress on the LEA protein family,noting that the number of its members varies significantly among different plant species,and they are classified into eight subgroups based on their structures.Meanwhile,LEA proteins exhibited high hydrophilicity,thermal stability,and diverse subcellular localization.Studies have shown that LEA proteins enhance plant stress resistance through mechanisms such as ion and reactive oxygen species(ROS)chelation,maintaining cell membrane stability,protecting protein/enzyme activity,and promoting biomolecular condensate formation.Addi-tionally,post-translational modifications(PTMs)such as phosphorylation could enhance LEA protein function,while lysine 2-hy-droxyisobutyrylation(Khib),an emerging PTM type,had been widely identified in plants and animals and may be associated with LEA protein-mediated stress tolerance mechanisms.Future research should further elucidate the role of LEA proteins in phase sepa-ration mechanisms and the specific functions of Khib modifications,to provide a theoretical basis for stress-resistant crop breeding and cell preservation technologies.关键词
LEA蛋白/蛋白质翻译后修饰/赖氨酸2-羟基异丁酰化Key words
Late embryogenesis abundant protein/Post-translational modifications/Lysine 2-hydroxyisobutyrylation分类
农业科技引用本文复制引用
何琦奇,苏晓艺,李汇泽,王瑞刚,李国婧..LEA蛋白家族及其作用机制研究进展[J].内蒙古农业大学学报（自然科学版）,2026,47(4):34-42,9.基金项目
国家自然科学基金项目(32160067) （32160067）
内蒙古自治区研究生科研创新项目(B20231081Z) （B20231081Z）
