器官移植2026，Vol.17Issue(5)：695-717,23.DOI:10.12464/j.issn.1674-7445.2026182
中国成人实体器官移植术后新发恶性肿瘤临床实践指南
Clinical practice guidelines on de novo malignancies after solid organ transplantation in adult in China
摘要
Abstract
With the continuous improvement of long-term survival rates among solid organ transplantation(SOT)recipients,de novo malignancy(DNM)following transplantation have become a critical factor impairing long-term prognosis and causing non-organ-failure-related mortality.The risk profile and disease spectrum of DNM vary across different types of SOT recipients,modulated by multiple factors including ethnicity,primary underlying diseases,intensity of immunosuppression,regional environmental conditions and patterns of viral infection.Distinct differences exist in demographic characteristics and cancer epidemiology between Chinese SOT recipients and their Western counterparts,rendering overseas evidence and recommendations not fully applicable to clinical practice in China.Against this backdrop,the Organ Transplantation Rehabilitation Committee of Chinese Association of Rehabilitation Medicine convened multidisciplinary experts to formulate the Clinical Practice Guidelines on De Novo Malignancies After Solid Organ Transplantation in Adult in China.Integrating domestic and international evidence-based medical data alongside real-world clinical experience in China,this guideline proposes clinical recommendations for risk assessment,screening,surveillance and management of post-transplant DNM specifically tailored to adult Chinese SOT recipients,so as to provide evidence-based references for clinical identification,monitoring and standardized management of DNM in this population.关键词
实体器官移植/新发恶性肿瘤/风险分层/肿瘤筛查/免疫抑制Key words
Solid organ transplantation/De novo malignancy/Risk stratification/Tumor screening/Immunosuppression分类
医药卫生引用本文复制引用
中国康复医学会器官移植康复专业委员会,张全保,陶一峰,沈丛欢,张彤,易述红,张剑峰,赵思捷,傅斌生,尚文俊,徐鑫,吴敏,邱江,李建华..中国成人实体器官移植术后新发恶性肿瘤临床实践指南[J].器官移植,2026,17(5):695-717,23.基金项目
国家重点研发计划(2023YFC2505900) （2023YFC2505900）
