器官移植2026,Vol.17Issue(5):718-730,13.DOI:10.12464/j.issn.1674-7445.2026138
肺移植术后慢性移植肺失功诊治专家共识(2025版)
Expert consensus on diagnosis and treatment of chronic lung allograft dysfunction after lung transplantation(2025 edition)
摘要
Abstract
Lung transplantation serves as an effective therapeutic option for end-stage pulmonary diseases.In recent years,the number of patients receiving lung transplantation in China has increased year by year.Nevertheless,chronic lung allograft dysfunction(CLAD),a major long-term complication following lung transplantation,remains a critical factor impairing the long-term survival of transplant recipients.To advance the development of lung transplantation in China and deliver comprehensive,safe,scientific and standardized diagnosis and treatment for relevant patients,the Lung Transplantation Group of Branch of Organ Transplantation of Chinese Medical Association invited thoracic surgery specialists from qualified lung transplant centers to collect extensive expert opinions.In accordance with evidence-based medicine principles and based on best available published Chinese and English clinical evidence available to date,this consensus has been formulated.It aims to resolve challenging issues in the diagnosis and treatment of post-transplant CLAD and to provide standardized clinical protocols for clinicians engaged in this field.关键词
肺移植/慢性移植肺失功/诊治/专家共识/闭塞性细支气管炎综合征/限制性移植物综合征/多学科团队Key words
Lung transplantation/Chronic lung allograft dysfunction/Diagnosis and treatment/Expert consensus/Bronchiolitis obliterans syndrome/Restrictive allograft syndrome/Multi-disciplinary team分类
医药卫生引用本文复制引用
中华医学会器官移植学分会肺移植学组,巨春蓉,田东,陈文慧,黄曼,郭璐,陈静瑜,何建行,吴波..肺移植术后慢性移植肺失功诊治专家共识(2025版)[J].器官移植,2026,17(5):718-730,13.基金项目
国家自然科学基金(82470103) (82470103)
广州医科大学科研能力提升计划(GMUCR2024-01007) (GMUCR2024-01007)
呼吸系统疾病国家重点实验室临床流行病学研究项目(SKLRD-L-202504) (SKLRD-L-202504)
中国医药教育协会项目(ZJWYH-2023-YIZHI-003) (ZJWYH-2023-YIZHI-003)
广州国家实验室-广州医科大学呼吸疾病全国重点实验室联合资助项目(GZNL2025B01002) (GZNL2025B01002)