四川精神卫生2026，Vol.39Issue(4)：303-308,317,7.DOI:10.11886/scjsws20260327001
不同自伤与自杀风险表型的抑郁症患者疼痛特征及其与风险表型的关系
Pain characteristics of patients with depression disorder across different self-injury/suicide risk phenotypes and their associations with the risk phenotypes
摘要
Abstract
Background Suicide and self-injury risk in patients with depression disorder is associated with pain symptoms,but the relationships between specific pain types and their severity and distinct self-injury/suicide risk phenotypes remain controversial.Objective To explore whether somatic pain can reflect different self-injury/suicide risk phenotypes,and to provide references for the clinical identification of suicide and self-injury risk in patients with depression.Methods Based on data from the National Survey on Symptomatology of Depression(NSSD),3 275 patients who met the diagnostic criteria for major depressive disorder in the Diagnostic and Statistical Manual of Mental Disorders,fourth edition,text revision(DSM-IV-TR)were recruited.According to previous suicidal behavior,suicidal ideation and self-injury behavior in the past two weeks,patients were divided into the no self-injury/suicide risk group,self-injury group,and high suicide-risk group.The occurrence of headache,muscle soreness,trunk pain,limb pain,and other pain symptoms was assessed using the structured symptom assessment instrument of the NSSD.With the no self-injury/suicide risk group as the reference,an ordinal Logistic regression model was used to analyze the associations between the risk groups and the occurrence frequency of pain,with demographic and clinical characteristics entered into the model as covariates for adjustment.Results A total of 3 211 patients(98.05%)were included in the analysis,including 1 329 cases(41.39%)in the no self-injury/suicide risk group,415 cases(12.92%)in the self-injury group,and 1 467 cases(45.69%)in the high suicide-risk group.Compared with the no self-injury/suicide risk group,the occurrence frequencies of headache(OR=1.526,95%CI:1.221-1.894)and muscle soreness(OR=1.287,95%CI:1.034-1.597)were higher in the self-injury group,and the occurrence frequencies of headache(OR=0.583,95%CI:0.504-0.672),muscle soreness(OR=0.682,95%CI:0.597-0.780),trunk pain(OR=0.557,95%CI:0.475-0.634),limb pain(OR=0.454,95%CI:0.384-0.522),and other pain difficult to localize(OR=0.542,95%CI:0.472-0.631)were all lower in the high suicide-risk group.Conclusion Patients with depression disorder across different self-injury and suicide risk phenotypes exhibit distinct pain characteristics,and these differences may provide a reference for the clinical identification of suicide and self-injury risk in patients with depression disorder.关键词
抑郁症/自杀风险/自伤行为/疼痛Key words
Depression disorder/Suicide risk/Self-injury behavior/Pain分类
医药卫生引用本文复制引用
卫千雪,粟幼嵩,黄佳,陈俊,方贻儒..不同自伤与自杀风险表型的抑郁症患者疼痛特征及其与风险表型的关系[J].四川精神卫生,2026,39(4):303-308,317,7.基金项目
"十三五"国家重点研发计划(项目名称:基于抑郁障碍临床病理特征的多维度诊断、个体化治疗及管理技术,项目编号:2016YFC1307100) （项目名称:基于抑郁障碍临床病理特征的多维度诊断、个体化治疗及管理技术,项目编号:2016YFC1307100）
上海市临床重点专科建设项目(项目名称:精神病与精神卫生) [Funded by The National Key Research and Development Program of China during the"13th Five-Year Plan"period(number,2016YFC1307100) （项目名称:精神病与精神卫生）
Shanghai Key Clinical Specialties Construction Project] （）
