摘要
Abstract
Objective:To explore the comparative value of ultrasound-guided fine-needle aspiration cytology(US-FNAC)and ultrasound-guided core-needle biopsy(US-CNB)in diagnosing cervical lymph node metastasis in lung cancer patients.Methods:The clinical data of 136 lung cancer patients diagnosed and treated from August 2018 to June 2022 were retrospec-tively selected.Using the final clinical diagnosis as the gold standard,71 cases were confirmed to have cervical lymph node metastasis,and both US-FNAC and US-CNB were performed prior to final confirmation.The concordance between the two methods and the gold standard was compared,and the ROC curve was constructed to analyze the AUC,sensitivity,and spe-cificity of US-FNAC and US-CNB in diagnosing cervical lymph node metastasis from lung cancer.Results:Of the 136 lung cancer patients,cervical lymph node metastasis was detected by US-FNAC in 59 cases(83.10%),including 15(83.33%)in zone Ⅲ,37(86.05%)in zone Ⅳ,and 7(70.00%)in zone VI,with a positive predictive value(PPV)of 100%and a negative predictive value(NPV)of 84.42%;by US-CNB,metastasis was detected in 69 cases(97.18%),including 18(100%)in zone Ⅲ,42(97.67%)in zone Ⅳ,and 9(90.00%)in zone VI,with a PPV of 100%and an NPV of 97.01%.Compared with the gold standard,US-FNAC showed good consistency(Kappa=0.825,P<0.05),and US-CNB also showed good consistency(Kappa=0.970,P<0.05).The diagnostic accuracy of US-CNB in detecting cervical lymph node metastasis was higher than that of US-FNAC(χ2=7.530,P=0.006).ROC curve analysis showed that the AUC of US-FNAC and US-CNB for diagnosing cervical lymph node metastasis from lung cancer were 0.915 and 0.986,respectively.The AUC of US-CNB was significantly higher than that of US-FNAC(Z=2.435,P=0.014).Conclusion:The detection rate of cervical lymph node metastasis from lung cancer using US-CNB is higher than that using US-FNAC.关键词
超声引导下细针穿刺细胞学/超声引导下粗针穿刺组织学/肺癌/颈部/淋巴结转移Key words
Ultrasound-guided fine-needle aspiration cytology/Ultrasound-guided core-needle biopsy for histology/Lung cancer/Neck/Lymph node metastasis分类
医药卫生
