生物加工过程2026，Vol.24Issue(4)：376-388,13.DOI:10.3969/j.issn.1672-3678.2026.04.004
酶催化固定CO2的气升式反应器中流体力学性能的优化
Optimization of fluid mechanical properties in three-phase airlift reactor for enzymatic CO2 fixation
摘要
Abstract
The three-phase 10-L airlift bioreactor system was investigated for its multi-enzyme catalytic CO2 fixation through both experiments and numerical simulations,evaluating the impact of design parameters on internal flow fields and overall volumetric mass transfer coefficient(kla).According to a computational fluid dynamics(CFD)model for the gas-liquid-solid three-phase system,which was established based on the conservation laws of mass and momentum under the Euler-Euler model,the k-ε turbulence model,as well as Higbie's penetration theory,the fluid flow and interphase mass transfer processes inside the reactor could be accurately simulated.Experimental results of the overall gas holdup and gas-liquid mass transfer coefficient kla showed less than 5％and 10％deviations compared with the predicted numbers by the model,demonstrating high credibility of this model.Moreover,with the superficial gas velocity in the range of 0.002 42-0.024 2 m/s,the reactor exhibited high gas holdup,suitable liquid velocity,as well as uniform distribution of solid particles under the optimal conditions when the solid holdup was 1％and the cross-sectional area ratio of riser to downcomer was 0.97.Our results provided valuable insights on the three-phase 10-L airlift bioreactor system for the development of enzymatic CO2 fixation,assisting the technology transfer from laboratory to industrial applications.关键词
酶/CO2固定/气升式反应器/计算流体力学Key words
enzyme/carbon dioxide fixation/airlift reactor/computational fluid dynamics分类
生物科学引用本文复制引用
刘果,AHMAD Salman,李柚西,张梦新,BELAISSAOUI Bouchra,张鑫,许海军,刘珞..酶催化固定CO2的气升式反应器中流体力学性能的优化[J].生物加工过程,2026,24(4):376-388,13.基金项目
国家重点研发计划(2022YFC2105900) （2022YFC2105900）
国家自然科学基金(22378015) （22378015）
