实用医学杂志2026，Vol.42Issue(16)：2926-2936,11.DOI:10.3969/j.issn.1006-5725.2026.16.008
电针抗抑郁作用的影像及分子机制的研究进展
Research advances in imaging and molecular mechanisms underlying the antidepressant effects of elec-troacupuncture
摘要
Abstract
Depression is a prevalent chronic and severe mental disorder characterized by structural and functional abnormalities in multiple brain regions that regulate emotion,cognition,and reward processing,alongside multiple molecular pathological alterations.As a non-pharmacological intervention,electroacupuncture has exhib-ited considerable therapeutic potential for depression treatment.Its antidepressant effects are not limited to a single brain region or molecular target;Instead,it exerts multi-level antidepressant actions by modulating abnormal brain activity and functional connectivity,which in turn influences neuroplasticity,inflammatory responses,and neurotransmitter release.Focusing on brain imaging findings and the molecular mechanisms underlying brain region-specific alterations,this article reviews functional brain abnormalities in depression and the neurobiological mechanisms underlying electroacupuncture intervention,with the aim of providing a theoretical foundation for mechanistic research and clinical application of electroacupuncture for depression treatment.关键词
电针/抑郁症/脑功能/影像Key words
electroacupuncture/depression/brain function/imaging分类
医药卫生引用本文复制引用
李虹莹,罗秋平,崔瑾,卢筱潇..电针抗抑郁作用的影像及分子机制的研究进展[J].实用医学杂志,2026,42(16):2926-2936,11.基金项目
国家自然科学基金项目(编号:82305390) （编号:82305390）
