实用中医药杂志2026,Vol.42Issue(8):1449-1451,3.DOI:10.3969/j.issn.1004-2814.2026.08.002
清肠止泻丸治疗腹泻型肠易激综合征临床研究
曾照富 1董靖1
作者信息
- 1. 河南省驻马店市中医院中医内科/脾胃科,河南 驻马店 463000
- 折叠
摘要
Abstract
Objective:To observe the therapeutic effect of Qingchang Zhixie Pills on diarrhea-predominant irritable bowel syndrome(IBS-D).Methods:Eighty patients were randomly divided into an observation group and a control group using a random number table,with 40 cases in each group.The control group received trimebutine maleate tablets,while the observation group received Qingchang Zhixie Pills.Both groups were treated continuously for 4 weeks.Results:The total effective rate in the observation group was higher than that in the control group(P<0.05).After treatment,both groups showed significant reductions in symptom scores,Irritable Bowel Syndrome Symptom Severity Scale(IBS-SSS)scores,serum 5-HT and IL-6 levels,and Bristol Stool Form Scale grades,while Irritable Bowel Syndrome Quality of Life(IBS-QOL)scores increased.The improvements in all indicators were superior in the observation group compared with the control group(P<0.05).Conclusion:Qingchang Zhixie Pills demonstrate good efficacy in treating IBS-D.关键词
腹泻型肠易激综合征/清肠止泻丸/对照治疗观察Key words
Diarrhea-predominant irritable bowel syndrome/Qingchang Zhixie Pills/Control treatment and observation分类
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曾照富,董靖..清肠止泻丸治疗腹泻型肠易激综合征临床研究[J].实用中医药杂志,2026,42(8):1449-1451,3.