天津中医药2026，Vol.43Issue(9)：1109-1114,6.DOI:10.11656/j.issn.1672-1519.2026.09.04
维持性血液透析合并肌少症的中医证候研究及相关影响因素分析
Study of traditional Chinese medicine syndromes in patients with maintenance hemodialysis combined with sarcopenia and analysis of related influencing factors
摘要
Abstract
[Objective]To investigate the characteristics of traditional Chinese medicine(TCM)syndrome patterns and their associated influencing factors in maintenance hemodialysis(MHD)patients complicated with sarcopenia.[Methods]In this single-center cross-sectional study,199 MHD patients were enrolled.Based on the 2019 Asian Working Group for Sarcopenia(AWGS)diagnostic criteria,patients were divided into a sarcopenia group and a non-sarcopenia group.Clinical data and TCM four diagnostic data were collected,and TCM syndrome patterns and identify associated risk factors were used to be statistical analysis.[Results]The prevalence rate of sarcopenia in this MHD cohort was 30.2%.Compared to the non-sarcopenia group,patients in the sarcopenia group were older,had a higher comorbidity index and prevalence of cerebral infarction,while exhibiting significantly lower body mass index(BMI),a lower proportion engaging in regular exercise,and reduced handgrip strength(P<0.05).Regarding TCM syndrome patterns,the primary pattern in both groups was spleen-kidney qi deficiency syndrome.The sarcopenia group had a significantly higher proportion of damp-turbidity syndrome(P<0.05),while the non-sarcopenia group had a higher proportion of blood stasis syndrome(P<0.05).Analysis of syndrome scores revealed that scores for spleen-kidney qi deficiency syndrome,spleen-kidney yang deficiency syndrome,and blood stasis syndrome were all significantly higher in the sarcopenia group compared to the non-sarcopenia group(P<0.05).Multivariate Logistic regression analysis indicated that advanced age,male gender and lack of exercise were risk factors for sarcopenia,while higher BMI,stronger handgrip strength and blood stasis syndrome were protective factors.[Conclusion]MHD patients with sarcopenia predominantly present with spleen-kidney qi deficiency as the primary pattern and internal obstruction by damp-turbidity as the secondary manifestation.Clinically,factors such as advanced age,male gender,and lack of exercise may increase the risk of sarcopenia in MHD patients.关键词
维持性血液透析/肌少症/中医证候/Logistic回归Key words
maintenance hemodialysis/sarcopenia/traditional Chinese medicine syndrome/Logistic regression分类
医药卫生引用本文复制引用
刘如馨,林帅,刘丽,徐娟,刘琳娜,庞捷,黄琳,黄清秀,李燕林..维持性血液透析合并肌少症的中医证候研究及相关影响因素分析[J].天津中医药,2026,43(9):1109-1114,6.基金项目
国家中医优势专科-中山市中医院肾病科([2024]2号) （[2024]2号）
国家中医药传承发展示范试点项目-中山市中医院中医药科研立项(YN2024A007) （YN2024A007）
国家中医药传承发展示范试点项目-中山市中医院潘胡丹教授高水平团队 （）
广州中医药大学附属中山中医院研究生及规培医师科研创新项目(2022KCY08). （2022KCY08）
