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Lactate metabolism and lactylation:Therapeutic and pre-clinical implications in neovascularization in peripheral artery disease

Sheng-Quan Chen Shu-Jing Zhang Pei-Jun Liu Yi Wu Si-Xuan Li Jian-Cang Ma Wu-Jun Li Shao-Ying Lu Ji-Chang Wang

药物分析学报（英文）2026，Vol.16Issue(4)：1014-1028,15.

药物分析学报（英文）2026，Vol.16Issue(4)：1014-1028,15.DOI:10.1016/j.jpha.2025.101457

Lactate metabolism and lactylation:Therapeutic and pre-clinical implications in neovascularization in peripheral artery disease

Sheng-Quan Chen ¹Shu-Jing Zhang ¹Pei-Jun Liu ²Yi Wu ³Si-Xuan Li ⁴Jian-Cang Ma ⁵Wu-Jun Li ⁶Shao-Ying Lu ¹Ji-Chang Wang¹

作者信息

1. Department of Vascular Surgery,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China
2. Center for Translational Medicine,The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710061,China
3. School of Basic Medicine,Xi'an Jiaotong University,Xi'an,710061,China
4. Department of Medicine,Xi'an Jiaotong University,Xi'an,710061,China
5. Department of Vascular Surgery,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,710001,China
6. Department of Vascular Surgery,The First Affiliated Hospital of Xi'an Medical University,Xi'an,710001,China
折叠

摘要

关键词

Peripheral artery disease/Neovascularization/Lactate/Lactylation/Ischemia

Key words

Peripheral artery disease/Neovascularization/Lactate/Lactylation/Ischemia

引用本文复制引用

Sheng-Quan Chen,Shu-Jing Zhang,Pei-Jun Liu,Yi Wu,Si-Xuan Li,Jian-Cang Ma,Wu-Jun Li,Shao-Ying Lu,Ji-Chang Wang..Lactate metabolism and lactylation:Therapeutic and pre-clinical implications in neovascularization in peripheral artery disease[J].药物分析学报（英文）,2026,16(4):1014-1028,15.

基金项目

This work is financially supported by Grants from the National Natural Science Foundation of China(Grant No.:82473146),the Outstanding Youth Science Fund of Shaanxi Province,China(Grant No.:2024JC-JCQN-80),the Fundamental Research Funds for the Central Universities,China(Grant No.:xzy012022094),and the Provincial Science and Technology Rising Star,China(Grant No.:2021KJXX-03). （Grant No.:82473146）

药物分析学报（英文）

ISSN：2095-1779

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