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Recent advances and expanding applications of organoid models in unveiling drug ADME profiles

Guolei Zhang Ruifan Zhang Zihang Shu Jing Zhao Lei Yin Meiyun Shi Yanshuo Han

药物分析学报（英文）2026，Vol.16Issue(6)：1633-1654,22.

药物分析学报（英文）2026，Vol.16Issue(6)：1633-1654,22.DOI:10.1016/j.jpha.2026.101676

Recent advances and expanding applications of organoid models in unveiling drug ADME profiles

Guolei Zhang ¹Ruifan Zhang ²Zihang Shu ²Jing Zhao ³Lei Yin ¹Meiyun Shi ¹Yanshuo Han¹

作者信息

1. Central Hospital of Dalian University of Technology,Dalian University of Technology,Dalian,Liaoning,116023,China||School of Chemical Engineering,Ocean and Life Sciences,Dalian University of Technology,Panjin,Liaoning,124221,China
2. School of Chemical Engineering,Ocean and Life Sciences,Dalian University of Technology,Panjin,Liaoning,124221,China
3. School of Chemical Engineering,Ocean and Life Sciences,Dalian University of Technology,Panjin,Liaoning,124221,China||Aim Honesty Biopharmaceutical Co.Ltd.,Dalian,Liaoning,116600,China
折叠

摘要

关键词

Organoids/Pharmacokinetics/ADME/In vitro models/Personalized medicine

Key words

Organoids/Pharmacokinetics/ADME/In vitro models/Personalized medicine

引用本文复制引用

Guolei Zhang,Ruifan Zhang,Zihang Shu,Jing Zhao,Lei Yin,Meiyun Shi,Yanshuo Han..Recent advances and expanding applications of organoid models in unveiling drug ADME profiles[J].药物分析学报（英文）,2026,16(6):1633-1654,22.

基金项目

This work was financially supported by the Natural Science Foundation of Liaoning Province(Grant Nos.:2023-MSBA-018,and 2025-MS-023),"Oncology+"Open Project of Liaoning Cancer Hospital(Project No.:2024-ZLKF-33),and the Fundamental Research Funds for the Central Universities(Grant No.:DUT24MS018). （Grant Nos.:2023-MSBA-018,and 2025-MS-023）

药物分析学报（英文）

ISSN：2095-1779

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