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首页|期刊导航|中国病毒学|Recent progress in anti-Chikungunya virus drug discovery:Focus on the viral life cycle and direct-acting antivirals

Recent progress in anti-Chikungunya virus drug discovery:Focus on the viral life cycle and direct-acting antivirals

Chunjiao Liu Shixiang Pan Mingxue Gao Yumin Zhang Leike Zhang Bin Lin Xiangrui Jiang

中国病毒学2026,Vol.41Issue(4):735-752,18.
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中国病毒学2026,Vol.41Issue(4):735-752,18.DOI:10.1016/j.virs.2026.07.001

Recent progress in anti-Chikungunya virus drug discovery:Focus on the viral life cycle and direct-acting antivirals

Recent progress in anti-Chikungunya virus drug discovery:Focus on the viral life cycle and direct-acting antivirals

Chunjiao Liu 1Shixiang Pan 2Mingxue Gao 3Yumin Zhang 4Leike Zhang 5Bin Lin 6Xiangrui Jiang7

作者信息

  • 1. Wuya College of Innovation,Shenyang Pharmaceutical University,Shenyang 110016,China||Shandong Laboratory of Yantai Drug Discovery,Bohai Rim Advanced Research Institute for Drug Discovery,Yantai 264117,China
  • 2. Shandong Laboratory of Yantai Drug Discovery,Bohai Rim Advanced Research Institute for Drug Discovery,Yantai 264117,China||Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China
  • 3. Shandong Laboratory of Yantai Drug Discovery,Bohai Rim Advanced Research Institute for Drug Discovery,Yantai 264117,China||School of Pharmacy,Anhui University of Traditional Chinese Medicine,Hefei 230012,China
  • 4. Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China
  • 5. Key Laboratory of Virology and Biosafety,Wuhan Institute of Virology,Chinese Academy of Sciences,Wuhan 430071,China||University of Chinese Academy of Sciences,Beijing 100049,China
  • 6. Wuya College of Innovation,Shenyang Pharmaceutical University,Shenyang 110016,China
  • 7. Shandong Laboratory of Yantai Drug Discovery,Bohai Rim Advanced Research Institute for Drug Discovery,Yantai 264117,China||Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China||University of Chinese Academy of Sciences,Beijing 100049,China
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摘要

关键词

Chikungunya virus(CHIKV)/Antiviral/Small molecule inhibitors/Structural proteins/Non-structural proteins

Key words

Chikungunya virus(CHIKV)/Antiviral/Small molecule inhibitors/Structural proteins/Non-structural proteins

引用本文复制引用

Chunjiao Liu,Shixiang Pan,Mingxue Gao,Yumin Zhang,Leike Zhang,Bin Lin,Xiangrui Jiang..Recent progress in anti-Chikungunya virus drug discovery:Focus on the viral life cycle and direct-acting antivirals[J].中国病毒学,2026,41(4):735-752,18.

基金项目

This work was supported by the Key R&D Program of Shandong Province,China(2025CXPT012,2024CXPT029),Shanghai Institute of Materia Medica,Chinese Academy of Sciences(SIMM0120231003),Yantai High-End Talent Introduction and Cultivation"Double-Hundred Plan"and the start-up funding(to X.J.)provided by Shandong Labora-tory of Yantai Drug Discovery,Bohai Rim Advanced Research Institute for Drug Discovery. (2025CXPT012,2024CXPT029)

中国病毒学

1003-5125

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