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Identification and characterization of anti-chikungunya virus compounds using a biosafe toolkit

Yang Gao Guojie Wang Hanhua Zhang Sicheng Tian Yanqun Wang Jincun Zhao Xing Liu Rong Ye Rong Zhang

中国病毒学2026，Vol.41Issue(4)：779-790,12.

中国病毒学2026，Vol.41Issue(4)：779-790,12.DOI:10.1016/j.virs.2026.08.005

Identification and characterization of anti-chikungunya virus compounds using a biosafe toolkit

Yang Gao ¹Guojie Wang ¹Hanhua Zhang ²Sicheng Tian ¹Yanqun Wang ³Jincun Zhao ³Xing Liu ²Rong Ye ¹Rong Zhang¹

作者信息

1. Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS),Shanghai Institute of Infectious Disease and Biosecurity,Shanghai Frontiers Science Center of Pathogenic Microorganisms and Infection,School of Basic Medical Sciences,Fudan University,Shanghai 200032,China
2. Guangdong Provincial Key Laboratory of Infection Immunity and Inflammation,Department of Pathogen Biology,Shenzhen University Medical School,Shenzhen 518060,China
3. State Key Laboratory of Respiratory Disease,National Clinical Research Center for Respiratory Disease,Guangzhou Institute of Respiratory Health,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510182,China
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摘要

关键词

Chikungunya virus(CHIKV)/Antiviral compound/Pseudovirus/Viral replicon particle/Replicon RNA

Key words

Chikungunya virus(CHIKV)/Antiviral compound/Pseudovirus/Viral replicon particle/Replicon RNA

引用本文复制引用

Yang Gao,Guojie Wang,Hanhua Zhang,Sicheng Tian,Yanqun Wang,Jincun Zhao,Xing Liu,Rong Ye,Rong Zhang..Identification and characterization of anti-chikungunya virus compounds using a biosafe toolkit[J].中国病毒学,2026,41(4):779-790,12.

基金项目

Grants from the Shanghai Municipal Science and Technology Major Project(ZD2021CY001),the Shenzhen Medical Research Fund,Shenz-hen,China(B2302029),the National Major Science and Technology Projects of China(2026ZD01908801),the National Natural Science Foundation of China(81974305,31970155),and the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences,China(2023-PT310-02)supported this work.The schematic diagrams in fig-ures,including Fig.1A and G,Fig.2A and B,Figs.3A,4A and 5A,were generated using BioRender(https://www.biorender.com/). （ZD2021CY001）

中国病毒学

ISSN：1003-5125

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