中国康复2026，Vol.41Issue(9)：515-520,6.DOI:10.3870/zgkf.2026.09.001
早中期帕金森病患者全维度注意功能特征及注意功能亚型分类研究
Characteristics of full-dimensional attention function and classification of attention function subtypes in patients with early-to-mid-stage Parkinson's disease
摘要
Abstract
Objective:To describe the characteristics of full-dimensional attention function changes in patients with early-to-mid stage Parkinson's disease(PD),explore classification based on attention function,and compare the differences in cognitive and motor functions among attention function subtypes.Methods:This was a cross-sectional study.A total of 112 patients with early-to-mid stage primary PD and 30 normal controls matched for sex,age,and years of education were enrolled.The digit span test,trail making test,stroop color-word test,and paced auditory serial addition test(PASAT)were used to assess each attention dimension.The mini-mental state examination and montreal cognitive assessment were used for global cognitive function,and the movement disorder society unified Parkinson's disease rating scale part Ⅲ was used to evaluate motor function.We analyzed the characteristics of atte-ntion function changes in each dimension,performed ex-ploratory cluster analysis to classify patients'attention function,and compared the differences in global cognition and motor function among subtypes.Results:There were 41 patients in the PD with cognitive impairment group,who showed significant differences from the PD with nor-mal cognition group and the normal control group in all at-tention dimension tests(P<0.05).In the 71 patients with PD and normal cognition,the errors in the trail making test and the interference amount of Stroop time con-sumption were significantly different from those of the normal control group(P<0.05).Exploratory cluster analy-sis suggested that PD patients might be classified into three types:high-transfer-high-allocation type,high-mainte-nance-balanced type,and low-transfer-low-selection type.Patients in the low-transfer-low-selection type had signifi-cantly lower global cognitive function and motor function than the other subtypes(P<0.05).Conclusion:Patients with early-to-mid stage PD show decline in attention selection and transfer functions,and other attention dimensions also decline as global cognitive function declines.The study observed that patients in the low-transfer-low-selection type had significantly lower global cognitive and motor functions than the other subtypes,providing preliminary evi-dence and a hypothesis worth testing for targeted assessment and treatment in future clinical work.关键词
帕金森病/注意功能/认知功能/分类Key words
Parkinson's disease/attention to functionality/cognitive function/classification分类
医药卫生引用本文复制引用
薛翠萍,陈可可,黄佩玲,张黎明,赵茹莲,方伯言..早中期帕金森病患者全维度注意功能特征及注意功能亚型分类研究[J].中国康复,2026,41(9):515-520,6.基金项目
国家重点研发计划(2022YFC3602603),首都医科大学附属北京康复医院引进人才科研启动基金(2023R-04) （2022YFC3602603）
