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青少年特发性脊柱侧凸预期姿势调节凸凹侧不对称性的多模态神经机制研究

黄家宝 张桂芳 陈子昱 张振发 陈春麟 王楚怀

中国康复2026,Vol.41Issue(9):533-539,7.
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中国康复2026,Vol.41Issue(9):533-539,7.DOI:10.3870/zgkf.2026.09.004

青少年特发性脊柱侧凸预期姿势调节凸凹侧不对称性的多模态神经机制研究

Multimodal investigation of anticipatory postural adjustments in AIS:Convex/concave asymmetry across central,pe-ripheral,and biomechanical dimensions

黄家宝 1张桂芳 1陈子昱 1张振发 1陈春麟 1王楚怀2

作者信息

  • 1. 中山大学附属第一医院康复医学科,广州 510080
  • 2. 中山大学附属第一医院康复医学科,广州 510080||广东省康复医学与临床转化工程技术研究中心
  • 折叠

摘要

Abstract

Objective:To investigate the central-peripheral-biomechanical features of anticipatory postural adjust-ments in adolescent idiopathic scoliosis(AIS)during a rapid arm raise task.Methods:Totally,38 subjects were en-rolled:11 healthy controls,14 mild AIS,and 13 moderate AIS.Participants performed rapid bilateral arm raises while 32-channel electroencephalography,surface electromyography of eight trunk muscles,and force platform cen-ter of pressure(COP)data were synchronously recorded.Single-trial EEG movement-related cortical potentials and event-related desynchronization were extracted using sEMG-detected movement onset as the temporal anchor and ag-gregated after group-level outlier cleaning.Statistical analysis combined trial-level linear mixed models with subject-level analysis of covariance in a hierarchical strategy.Results:The mild group showed lower convex-side paraspinal integrated EMG than the concave side,whereas the moderate group exhibited a reversed pattern with high-energy convex-side compensation(P=0.006).Movement-related cortical potential amplitude followed an health control>mild>moderate gradient(P=0.018).Body mass index independently modulated both central motor preparation timing and peripheral postural mechanical output(P=0.007).Thoracic-curve sensitivity analysis confirmed these findings.Conclusion:The primary APA abnormality in AIS is convex/concave paraspinal energy maldistribution that worsens during repeated rapid movements.BMI may modulate both cortical preparation timing and biomechani-cal postural output through inertial loading.Convex/concave mapping combined with synchronized EEG-sEMG-COP analysis may help characterize neuromuscular control deficits in AIS and may provide a basis for individualized fatigue-aware rehabilitation assessment.

关键词

青少年特发性脊柱侧凸/预期姿势调节/椎旁肌不对称/事件相关去同步化/姿势控制/凸/凹侧映射

Key words

adolescent idiopathic scoliosis/anticipa-tory postural adjustments/paraspinal muscle asymme-try/event-related desynchronization/postural control/convex/concave mapping

分类

医药卫生

引用本文复制引用

黄家宝,张桂芳,陈子昱,张振发,陈春麟,王楚怀..青少年特发性脊柱侧凸预期姿势调节凸凹侧不对称性的多模态神经机制研究[J].中国康复,2026,41(9):533-539,7.

基金项目

国家自然科学基金(82172532) (82172532)

广东省康复医学临床医学研究中心项目(2023B110003) (2023B110003)

中国康复

1001-2001

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