中国康复理论与实践2026，Vol.32Issue(9)：1041-1051,11.DOI:10.3969/j.issn.1006-9771.2026.09.006
实时与视频动作观察疗法下脑卒中患者脑区血氧动力学反应比较:一项基于功能性近红外光谱的研究
Comparison of cortical hemodynamic responses between real-time and video-based action observation therapy in patients with stroke:a functional near-infrared spectroscopy study
摘要
Abstract
Objective To investigate the hemodynamic differences in cortical activation during the observation-imitation process be-tween real-time action observation therapy(R-AOT)and video-based action observation therapy(V-AOT)in pa-tients with stroke using functional near-infrared spectroscopy(fNIRS). Methods A total of 29 patients with stroke in Shanxi Bethune Hospital from June to September,2025 were enrolled.A randomized-sequence,self-controlled crossover trial design was employed.Each participant received both R-AOT and V-AOT,with a one-day interval between the two conditions to minimize potential carryover effect.fNIRS was used to simultaneously record changes in oxyhemoglobin(Oxy-Hb)concentration during the observa-tion and imitation phases in regions of interest(ROIs),including the ipsilesional and contralesional dorsolateral prefrontal cortex(DLPFC),occipital cortex(OC),and temporal cortex(TC). Results After false discovery rate(FDR)correction across all ROIs,no significant difference was observed between R-AOT and V-AOT during either the observation or imitation phase(PFDR>0.05).During the observation phase,Oxy-Hb was greater under R-AOT than under V-AOT in the ipsilesional DLPFC(Z=2.183,PFDR=0.045).Oxy-Hb showed an opposite directional pattern between the two conditions in the ipsilesional OC,but the difference was not statistically significant(Z=2.321,PFDR=0.060).During the imitation phase,the ipsilesional TC showed greater Oxy-Hb changes under R-AOT than under V-AOT(Z=2.724,PFDR=0.018). Conclusion R-AOT and V-AOT may elicit different local cortical hemodynamic responses during the observation and imitation phases in patients with stroke.The between-condition difference during the observation phase was mainly observed in the ipsilesional DLPFC,whereas during the imitation phase it was mainly observed in the ip-silesional TC.关键词
脑卒中/实时动作观察疗法/视频动作观察疗法/功能性近红外光谱/皮质激活/镜像神经元系统Key words
stroke/real-time action observation therapy/video-based action observation therapy/functional near-infrared spectroscopy/cortical activation/mirror neuron system分类
医药卫生引用本文复制引用
黄旭丽,王萍芝,罗天娥..实时与视频动作观察疗法下脑卒中患者脑区血氧动力学反应比较:一项基于功能性近红外光谱的研究[J].中国康复理论与实践,2026,32(9):1041-1051,11.基金项目
1.山西省研究生教育创新计划项目(No.2025xx13) （No.2025xx13）
2.山西医科大学教育教学研究项目(No.XJ2025176) （No.XJ2025176）
3.山西省重点研发计划项目(No.202302130501014) Supported by Graduate Education Innovation Program Project of Shanxi Province(No.2025xx13),Shanxi Medical University Educational and Teaching Research Project(No.XJ2025176),and Shanxi Provincial R&D Program(Key)(No.202302130501014) （No.202302130501014）
