中国普通外科杂志2026，Vol.35Issue(7)：1269-1286,18.DOI:10.7659/j.issn.1005-6947.260182
肝性骨病诊疗中国专家共识(2026年版)
Chinese expert consensus on the diagnosis and management of hepatic osteodystrophy(2026 edition)
摘要
Abstract
Hepatic osteodystrophy(HOD)is a metabolic bone disorder that occurs in patients with chronic liver disease or following liver transplantation,and is primarily characterized by osteoporosis and/or osteomalacia.Owing to the heterogeneous etiologies of chronic liver diseases,HOD exhibits substantial clinical heterogeneity,making early diagnosis challenging and leading to frequent underrecognition in clinical practice.To date,no universally accepted guideline is available for the diagnosis and management of HOD.The Chinese Medical Association's Medical Cell Biology Branch,Jiangsu Research Hospital Society,Jiangsu Development Biology Society,and Jiangsu Surgical Physicians Association convened a multidisciplinary panel of experts in hepatology,orthopedics,radiology,laboratory medicine,and basic medical sciences.Based on a systematic review of the latest national and international evidence and informed by current clinical practice in China,the panel developed 31 expert recommendations addressing key issues,including the epidemiology,risk factors,pathogenesis,screening and prevention,diagnosis and differential diagnosis,treatment,and follow-up management of HOD,and formulated the Chinese expert consensus on the diagnosis and management of hepatic osteodystrophy(2026 edition).This consensus aims to provide evidence-informed recommendations for the standardized screening,diagnosis,treatment,and long-term management of HOD,thereby improving clinical outcomes and quality of life in affected patients.关键词
骨疾病,代谢性/肝性骨病/诊断/肝性骨病/治疗/多数赞同Key words
Bone Diseases,Metabolic/Hepatic Osteodystrophy/diag/Hepatic Osteodystrophy/ther/Consensus分类
医药卫生引用本文复制引用
中华医学会医学细胞生物学分会,江苏省研究型医院学会,江苏省发育生物学会,江苏省医师协会外科分会,薛斌,吕凌,秦锡虎,秦磊..肝性骨病诊疗中国专家共识(2026年版)[J].中国普通外科杂志,2026,35(7):1269-1286,18.基金项目
国家自然科学基金资助项目(32271187,32300646,32571329) （32271187,32300646,32571329）
中国科学技术部基金资助项目(2024YFA1107700,2024YFA1107704) （2024YFA1107700,2024YFA1107704）
江苏省自然科学基金项目青年基金资助项目(BK20230300) （BK20230300）
新疆维吾尔自治区自然科学基金资助项目(2023D01D05) （2023D01D05）
江苏省卫生健康委医学科研基金资助项目(H2023103) （H2023103）
高水平医院科技创新支撑计划应用基础研究基金资助项目(KJCXQ2024012). （KJCXQ2024012）
