中国全科医学2026，Vol.29Issue(32)：4716-4720,5.DOI:10.12114/j.issn.1007-9572.2026.0043
机会性筛查人群胃癌前状态检出现状及影响因素研究
Analysis of the Current Situation and Influencing Factors of Gastric Precancerous Conditions in Opportunistic Screening Populations
杨新颖 1王凯蓉 1李俊 1叶凡婷 1王梦瑶 1李宾宾1
作者信息
- 1. 100730 北京市,中国医学科学院北京协和医学院 北京协和医院国际医疗部
- 折叠
摘要
Abstract
Background Gastric precancerous conditions(GPC),including gastric mucosal atrophy and intestinal metaplasia,represent a critical and intervenable stage in the development of gastric cancer.Opportunistic screening serves as an important supplementary model for secondary prevention of gastric cancer in China.However,studies on the detection rate and influencing factors of GPC in opportunistic screening populations are relatively limited.Objective To analyze the detection status of GPC in an opportunistic screening population and to explore related influencing factors,thereby providing evidence-based support for clinicians to accurately identify high-risk individuals and to develop personalized health management strategies.Methods Using convenience sampling,patients undergoing opportunistic screening at Peking Union Medical College Hospital from March to July 2024 were enrolled.Data were collected using a general information questionnaire and the Chinese population gastric cancer risk scoring system(GC-RSS).GPC was determined based on pathological findings from gastroscopic biopsies.Multivariate Logistic regression analysis was performed to identify independent influencing factors for GPC.Results A total of 304 questionnaires were distributed,and 301 valid questionnaires were retrieved,with an effective response rate of 99.0%.Among the 301 patients,the detection rate of GPC was 24.6%(74/301).Multivariate Logistic regression analysis showed that the GC-RSS≥5(OR=2.124,95%CI=1.220-3.698,P<0.05)and previous history of gastric diseases(OR=2.036,95%CI=1.135-3.650,P<0.05)were independent influencing factors for the presence of GPC.Conclusion The detection rate of GPC in the opportunistic screening population is relatively high.Previous history of gastric diseases and GC-RSS≥5 can be used as key indicators for risk stratification.This study provides a preliminary validation of the good predictive value of the GC-RSS in this population.As a non-invasive risk assessment tool,GC-RSS can be used for rapid preliminary screening in general practice clinics or health management processes,thereby advancing the prevention and control of gastric cancer forward to the precancerous stage.关键词
癌前状态/胃黏膜/机会性筛查/影响因素分析Key words
Precancerous conditions/Gastric mucosa/Opportunistic screening/Root cause analysis分类
医药卫生引用本文复制引用
杨新颖,王凯蓉,李俊,叶凡婷,王梦瑶,李宾宾..机会性筛查人群胃癌前状态检出现状及影响因素研究[J].中国全科医学,2026,29(32):4716-4720,5.
