中国实用儿科杂志2026，Vol.41Issue(8)：637-639,3.DOI:10.19538/j.ek2026080604
从广谱抑制到精准靶向
From broad-spectrum suppression to precision targeting:the paradigm shift and challenges in the treatment of pediatric rheumatic and immune diseases
摘要
Abstract
With rapid advancements in immunology,molecular biology,and targeted drug development,the treatment for pediatric rheumatic and immune diseases has undergone a profound paradigm shift within just a few decades—from the non-specific approach of"broad-spectrum immunosuppression"as a last resort to a thriving era characterized by"precision targeted therapy"targeting specific inflammatory pathways or key molecules.This fundamental shift in therapeutic philosophy not only provides multiple treatment options for affected children but also significantly improves their clinical outcomes and quality of life.关键词
风湿免疫病/药物治疗/儿童Key words
rheumatic and immune diseases/pharmacotherapy/child分类
医药卫生引用本文复制引用
钟林庆,宋红梅..从广谱抑制到精准靶向[J].中国实用儿科杂志,2026,41(8):637-639,3.基金项目
中央高水平医院临床科研专项基金(2025-PUMCH-C-047) （2025-PUMCH-C-047）
