中国实用外科杂志2026，Vol.46Issue(8)：1055-1058,1076,5.DOI:10.19538/j.cjps.issn1005-2208.2026.08.09
动脉预阻断技术在局部进展期胰腺癌手术中应用
Application of arterial prophylactic occlusion technique in surgery for locally advanced pancreatic cancer
摘要
Abstract
Locally advanced pancreatic cancer(LAPC)accounts for approximately 30％of newly diagnosed pancreatic cancer cases,with arterial involvement representing the foremost surgical barrier to curative resection.The recent progress in neoadjuvant therapy has rendered an increasing subset of these patients eligible for conversion surgery;nevertheless,the post-conversion procedure frequently remains encumbered by dense tumor adherence to major arterial walls.Arterial sheath resection-achieving R0 clearance via meticulous dissection along the anatomical plane between the adventitia and the external elastic lamina without sacrificing the underlying artery-has emerged as the preferred approach for managing arterial-involved LAPC.Based on this foundation,the arterial prophylactic occlusion technique(APOT)enhances the safety of sheath dissection through intraoperative temporary and graded flow control of the affected artery.APOT is indicated during arterial sheath dissection after neoadjuvant therapy;by providing graded temporary flow control,it can shorten operative time,reduce blood loss,achieve an R0 resection rate of 85.7％,and does not increase complications.关键词
局部进展期胰腺癌/动脉鞘剥除技术/动脉预阻断技术/动脉切除重建/新辅助治疗Key words
locally advanced pancreatic cancer/arterial sheath resection/arterial prophylactic occlusion technique/arterial resection and reconstruction/neoadjuvant therapy分类
医药卫生引用本文复制引用
金钢,郑楷炼,经纬,时霄寒,高绥之,汪超..动脉预阻断技术在局部进展期胰腺癌手术中应用[J].中国实用外科杂志,2026,46(8):1055-1058,1076,5.基金项目
National Science and Technology Major Project for Prevention and Treatment of Cancer,Cardiovascu-lar,Respiratory,and Metabolic Diseases(No.2025ZD0552306) （No.2025ZD0552306）
General Incubation Program of Basic Medical Research of Naval Medical University(No.2022MS013) 癌症、心脑血管、呼吸和代谢性疾病防治研究国家科技重大专项(No.2025ZD0552306) （No.2022MS013）
海军军医大学校级基础医学研究课题面上孵化项目(No.2022MS013) （No.2022MS013）
