中国癌症防治杂志2026，Vol.18Issue(4)：427-433,7.DOI:10.27054/j.cnki.ISSN.1674-5671.2026.04.05
2010-2019年武汉市脑及中枢神经系统恶性肿瘤死亡率及早死寿命损失年变化趋势分析
Trends in mortality and years of life lost due to malignant tumors of the brain and central nervous system in Wuhan,2010-2019
摘要
Abstract
Objective To analyze the mortality level and premature death burden of malignant tumors of the brain and central nervous system among residents in Wuhan from 2010 to 2019 and to provide evidence for formulating intervention strategies.Methods Data on deaths caused by malignant tumors of the brain and central nervous system in Wuhan during 2010-2019 were collected.Crude mortality rate(CMR),age-standardized mortality rate by the Chinese population(ASMRC),years of life lost(YLL),average years of life lost(AYLL),and age-standardized years of life lost rate(ASYLLR)were calculated to evaluate the mortality burden.Joinpoint regres-sion was adopted to estimate the annual percent change(APC)and average annual percent change(AAPC)for trend analysis.Results The CMR and ASMRC of malignant tumors of the brain and central nervous system among Wuhan residents were 4.90/105 and 3.94/105,respectively,during 2010-2019.By sex,the CMR and ASMRC were 5.29/105 and 4.33/105 for males,and 4.49/105 and 3.54/105 for females.By urban/rural residence,the CMR and ASMRC were 3.94/105 and 3.03/105 in urban areas,versus 6.01/105 and 5.59/105 in rural areas.The overall mortality remained stable without obvious fluctuations throughout the study period.At the gender level,the CMR for both sexes and ASMRC for males showed stable trends(all P>0.05),whereas only female ASMRC presented a significant downward trend(APC=-1.44％,P=0.04).At the urban rural level,only rural CMR exhibited an upward trend(P=0.08),while changes in urban CMR and both urban and rural ASMRC were not statistically significant(all P>0.05).The YLL was 12,134.38 years,with an AYLL of 31.33 years per decedent and an ASYLLR of 135.75 years per 105.Over the decade,YLL showed an upward trend,whereas no obvious temporal fluctuation was observed for AYLL or ASYLLR.Age stratified analysis indicated that mortality from malignant tumors of the brain and central nervous system increased significantly with age.Conclusions The overall mortality of malignant tumors of the brain and central nervous system remained stable among Wuhan residents from 2010 to 2019,while the burden of years of life lost due to premature death increased.Males,rural residents,and the elderly should be prioritized for screening and intervention programs targeting malignant tumors of the brain and central nervous system in Wuhan.关键词
脑及中枢神经系统恶性肿瘤/死亡率/趋势/早死寿命损失年Key words
Malignant tumors of the brain and central nervous system/Mortality/Trend/Years of life lost分类
医药卫生引用本文复制引用
赵原原,代娟,邓青,张晓霞,熊金梦,刘普林..2010-2019年武汉市脑及中枢神经系统恶性肿瘤死亡率及早死寿命损失年变化趋势分析[J].中国癌症防治杂志,2026,18(4):427-433,7.基金项目
老年健康体检队列和重大慢病专病数据库建设与应用研究项目(WX32Z95) （WX32Z95）
