中国中西医结合影像学杂志2026，Vol.24Issue(5)：570-575,6.DOI:10.3969/j.issn.1672-0512.2026.05.009
基于心血管磁共振特征追踪技术的左室整体纵向应变对疑似冠心病患者长期预后的预测价值
Predictive value of left ventricular global longitudinal strain based on cardiovascular magnetic resonance feature tracking technology for long-term prognosis in patients with suspected coronary artery disease
摘要
Abstract
Objective:To investigate the long-term predictive value of left ventricular global longitudinal strain(GLS),derived from cardiovascular magnetic resonance feature tracking(CMR-FT),for major adverse cardiovascular events(MACE)in patients with suspected coronary artery disease(CAD).Methods:This study enrolled 189 patients with suspected CAD,who underwent cardiovascular magnetic resonance(CMR)within 72 hours of admission.The CMR protocol included magnetic resonance coronary angiography(MRCA),and late gadolinium enhancement scan.Based on the degree of coronary stenosis,patients were divided into an obstructive CAD group(n=106)and a non-obstructive CAD group(n=83).Clinical data and CMR parameters were compared between the two groups.Univariate and multivariate Cox regression analyses were used to identify independent predictors of MACE.ROC curves were plotted to evaluate the predictive performance of these independent predictors,and patients were stratified according to cutoff values for survival comparisons.The incremental predictive value of GLS was assessed using the C-statistic.Results:The obstructive CAD group was older and had higher proportions of males and smokers compared with the non-obstructive CAD group(all P<0.05).The proportions of patients with late gadolinium enhancement(LGE)and transmural myocardial infarction(TMI)were higher,while the absolute value of GLS was lower in the obstructive CAD group than in the non-obstructive CAD group(all P<0.05).During follow-up,49 patients experienced MACE.Univariate Cox regression analysis identified hyperlipidemia,LGE,TMI,and GLS as predictors of MACE(all P<0.05).Multivariate Cox regression analysis demonstrated that TMI and GLS were independent predictors of MACE(both P<0.05).The AUC of GLS for predicting MACE was 0.80.Adding GLS to TMI increased the C-statistic by 0.197 for predicting MACE.Conclusion:In patients with suspected CAD,TMI and GLS have independent predictive value for MACE,and GLS provides incremental predictive value.关键词
磁共振成像/心室功能,左/冠状动脉疾病,预后/特征追踪/整体纵向应变Key words
Magnetic resonance imaging/Ventricular function,left/Coronary artory disease/Prognosis/Feature tracking/Global longitudinal strain分类
医药卫生引用本文复制引用
晏乘曦,李瑞利,张莉,樊佳怡,徐增苗,雷朝,张新军,代双凤,张月浪,常莹..基于心血管磁共振特征追踪技术的左室整体纵向应变对疑似冠心病患者长期预后的预测价值[J].中国中西医结合影像学杂志,2026,24(5):570-575,6.基金项目
国家自然科学基金项目(82202118). （82202118）
