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芬太尼预处理对小儿扁桃体腺样体切除术后苏醒期躁动、镇静效果及早期呼吸系统不良事件的影响

赵增晓 魏巍 杨婷 邱永升 贾英萍

中国合理用药探索2026,Vol.23Issue(8):50-56,7.
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中国合理用药探索2026,Vol.23Issue(8):50-56,7.DOI:10.3969/j.issn.2096-3327.2026.08.008

芬太尼预处理对小儿扁桃体腺样体切除术后苏醒期躁动、镇静效果及早期呼吸系统不良事件的影响

Effects of Fentanyl Pretreatment on Emergence Agitation,Sedation,and Early Respiratory Adverse Events in Children Undergoing Tonsillectomy and Adenoidectomy

赵增晓 1魏巍 1杨婷 1邱永升 1贾英萍1

作者信息

  • 1. 郑州大学附属儿童医院/河南省儿童医院郑州儿童医院麻醉与围术期医学科,郑州 450018
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摘要

Abstract

Objective:To investigate the effects of fentanyl pretreatment on emergence agitation,sedation,and early respiratory adverse events in children undergoing tonsillectomy and adenoidectomy.Methods:A total of 82 children scheduled to undergo tonsillectomy and adenoidectomy at our hospital between August 2021 and December 2023 were assigned according to block randomization to a control group or a study group,with 41 patients in each group.At induction of anesthesia,the control group received an intravenous injection of sodium chloride,while the study group received an intravenous injection of fentanyl citrate.Thereafter,both groups underwent induction and maintenance of anesthesia,and the infusion was discontinued at the end of surgery.Perioperative recovery variables,sedation[assessed using the Ramsay Sedation Scale],emergence agitation[assessed using the Pediatric Anesthesia Emergence Delirium Scale(PAED)],and the incidence of early respiratory adverse events were compared between the groups.Results:No significant between-group differences were observed in time to emergence,length of stay in the postanesthesia care unit,Face,Legs,Activity,Cry,Consolability(FLACC)Scale scores at postanesthesia care unit discharge or on postoperative day 2,time to oral fluid or food intake on the ward,or time to discharge(P>0.05).At 10,30,and 60 min after extubation,Ramsay Sedation Scale scores were higher and PAED scores were lower in the study group than in the control group(P<0.05).The overall incidence of early respiratory adverse events did not differ significantly between the groups(P>0.05).Conclusion:Fentanyl pretreatment may be an effective strategy for improving the quality of emergence after tonsillectomy and adenoidectomy in children.

关键词

扁桃体腺样体切除术/小儿/苏醒期躁动/镇静效果/呼吸功能

Key words

tonsillectomy and adenoidectomy/children/emergence agitation/sedation/respiratory function

分类

医药卫生

引用本文复制引用

赵增晓,魏巍,杨婷,邱永升,贾英萍..芬太尼预处理对小儿扁桃体腺样体切除术后苏醒期躁动、镇静效果及早期呼吸系统不良事件的影响[J].中国合理用药探索,2026,23(8):50-56,7.

中国合理用药探索

2096-3327

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