中国中医药信息杂志2026，Vol.33Issue(9)：38-47,10.DOI:10.19879/j.cnki.1005-5304.202602275
基于复杂网络分析针灸治疗卒中后抑郁的临床应用规律
Analysis on Clinical Application Law of Acupuncture and Moxibustion for Post-stroke Depression Based on Complex Network Analysis
摘要
Abstract
Objective To analyze the core acupoint prescriptions and clinical application law of acupuncture in the treatment of post-stroke depression(PSD)based on complex network analysis.Methods Literature about acupuncture and moxibustion for the treatment of PSD was retrieved from databases including CNKI,Wanfang Data,VIP,Web of Science,and PubMed from their inception to January 1,2026.After screening based on inclusion and exclusion criteria,relevant information was extracted.A descriptive summary was conducted for acupoint frequency,meridian tropism,body regions,specific acupoints,intervention methods,and specialized acupuncture techniques.Association rule analysis for main acupoints was performed using the Apriori algorithm in IBM SPSS Modeler 18.0.OriginPro2026 software was used for clustering analysis,while Cytoscape 3.10.0 software was used for visualization of the main acupoints and syndrome classification-matching acupoints.Results A total of 397 articles were included,yielding 672 prescriptions involving 234 acupoints(including characteristic acupuncture zones),with a total frequency of 3 338 times.The top 10 high-frequency acupoints were Baihui(GV20),Neiguan(PC6),Taichong(LR3),Sanyinjiao(SP6),Shenmen(HT7),Yintang(EX-HN3),Sishencong(EX-HN1),Shenting(GV24),Zusanli(ST36),and Hegu(LI4).Acupoints predominantly belonged to the Governor Vessel and the bladder meridian of foot-taiyang.The head/neck and lower limb regions were most commonly used.Intersection points and Five-Shu acupoints were the primary specific acupoint categories.Acupuncture combined with Western medicine was the main intervention for PSD in clinical practice.Among characteristic acupuncture therapies,scalp acupuncture,ear acupuncture,and eye acupuncture were used most frequently.Association rule analysis indicated the highest support for the combinations of Baihui-Neiguan,Baihui-Taichong-Neiguan,Neiguan-Shenmen-Taichong-Baihui,and Taichong-Yintang-Shenmen-Neiguan-Baihui.Clustering analysis grouped acupoints with a frequency>20 into 6 categories.The main syndromes were liver qi stagnation syndrome,heart-spleen deficiency syndrome,qi stagnation transforming into fire syndrome,phlegm-qi stagnation syndrome,yin deficiency with effulgent fire syndrome,melancholy injuring the spirit syndrome,liver-kidney yin deficiency syndrome,and liver-kidney depletion syndrome.Conclusion The core acupoint prescriptions of acupuncture and moxibustion for the treatment of PSD consist of Baihui(GV20),Neiguan(PC6),Taichong(LR3),Shenmen(HT7),Yintang(EX-HN3),and Sishencong(EX-HN1).The therapeutic approach emphasizes awakening the brain and calming the spirit,nourishing the heart and soothing the liver,with equal importance placed on physical and psychological aspects.关键词
卒中后抑郁/针灸/复杂网络分析Key words
post-stroke depression/acupuncture and moxibustion/complex network analysis分类
医药卫生引用本文复制引用
李冰枝,肖洪波,杨雅淇,朱宗俊,李梦醒,许倩文,卢盼,杨楠,王雅,管媛媛..基于复杂网络分析针灸治疗卒中后抑郁的临床应用规律[J].中国中医药信息杂志,2026,33(9):38-47,10.基金项目
国家自然科学基金青年科学基金项目(82305361) （82305361）
国家中医药管理局中医康复中心建设单位(2023年) （2023年）
安徽省科技厅临床医学研究转化专项(202304295107020101) （202304295107020101）
