植物保护学报2026，Vol.53Issue(4)：869-880,12.DOI:10.13802/j.cnki.zwbhxb.2026.2026823
小菜蛾对Bt Cry1Ac杀虫蛋白抗性的遗传与信号调控机制
Genetic and signaling regulatory mechanisms underlying resistance to the Bt Cry1Ac toxin in the diamondback moth Plutella xylostella
摘要
Abstract
Cruciferous vegetables are among the most important vegetable crops in China.They are not only a core component of the national vegetable supply system but also play a crucial role in seed indus-try revitalization,rural development,and functional agriculture.The diamondback moth Plutella xylo-stella is a major pest of cruciferous vegetables and causes substantial economic losses to agricultural production each year.Bacillus thuringiensis(Bt)produces a variety of insecticidal proteins,including Cry1Ac,which have been widely used for the control of P.xylostella because of their high efficacy,target specificity,and environmental safety.However,the evolution of resistance to the Bt Cry1Ac toxin in P.xylostella has greatly reduced the effectiveness of Bt-based pest control.This review summarizes the resistance mechanisms of P.xylostella to Bt Cry1Ac toxin,with particular emphasis on resistance evolution mediated by alterations in midgut receptors and signaling pathways.Future research direc-tions are also discussed,highlighting the need to integrate modern genetics,molecular biology,and multi-omics approaches to further elucidate the molecular mechanisms underlying Bt resistance.关键词
小菜蛾/苏云金芽胞杆菌/Cry杀虫蛋白/抗性机制/信号途径Key words
Plutella xylostella/Bacillus thuringiensis/Cry toxin/resistance mechanism/signaling path-way引用本文复制引用
龚莉君,康师,钟杨,郭兆将..小菜蛾对Bt Cry1Ac杀虫蛋白抗性的遗传与信号调控机制[J].植物保护学报,2026,53(4):869-880,12.基金项目
湖北科技学院博士启动基金项目(BK202114),湖北省教育厅科学技术研究项目(Q20232807),国家自然科学基金项目(32372600,32372545),中国农业科学院科技创新工程项目(CAAS-CSCB-202303) （BK202114）
