中国现代医生2026，Vol.64Issue(24)：24-34,43,12.DOI:10.3969/j.issn.1673-9701.2026.24.006
基于随机对照试验的一项关于益生菌对血压影响的Meta分析
A Meta-analysis of the effects of probiotics on blood pressure based on randomized controlled trials
赵栩进 1王云俊 1郭冬娜1
作者信息
- 1. 山西医科大学第一医院急诊医学中心,山西 太原 030001
- 折叠
摘要
Abstract
Objective To systematically review the relationship between probiotics and blood pressure.Methods The PubMed(MEDLINE),Embase,Web of Science,Cochrane Library,China National Knowledge Infrastructure,Wanfang Data Knowledge Service Platform were searched to collect randomized controlled trials included the relationship between probiotics and blood pressure,with the search period ranging from database establishment to February 1,2026.Two researchers independently screened the literature,extracted data,and assessed the risk of bias in the included studies,followed by a Meta-analysis using RevMan 5.4.1 software.Results A total of 23 articles were included.Meta-analysis results showed that using probiotics preparations can significantly reduce diastolic pressure compared with control group.Subgroup analysis showed that whether the intervention duration was greater than or equal to 8 weeks might be a source of heterogeneity,while whether it was a single strain or whether it is a hypertensive population are not a factor affecting heterogeneity.Conclusion Probiotics intervention has a positive effect on controlling blood pressure,especially diastolic blood pressure.Due to the limitations in the number and quality of included studies,the above conclusions still need to be verified by more high-quality research.关键词
高血压/肠道微生态/益生菌Key words
Hypertension/Gut microecology/Probiotics分类
医药卫生引用本文复制引用
赵栩进,王云俊,郭冬娜..基于随机对照试验的一项关于益生菌对血压影响的Meta分析[J].中国现代医生,2026,64(24):24-34,43,12.
