中医杂志2026，Vol.67Issue(17)：1853-1857,5.DOI:10.13288/j.11-2166/r.2026.17.009
基于临床实践指南的中西医诊疗智能体构建的方法学思考
Methodological Considerations on Constructing Intelligent Diagnosis and Treatment Agent for Integrated Chinese and Western Medicine Diagnosis and Treatment Based on Clinical Practice Guidelines
摘要
Abstract
Developing an intelligent agent for integrated traditional Chinese and western medicine diagnosis and treatment based on clinical practice guidelines is a key approach to advancing the standardization and intelligent deve-lopment of traditional Chinese medicine(TCM)and to supporting clinical decision-making.This paper argues for the necessity of building a knowledge base using guidelines as the sole data source,systematically identifies five core methodological challenges across the entire process,and proposes corresponding solutions.An ontology framework capable of distinguishing between TCM and western medicine concepts should be designed to address the difficulty of knowledge integration.A closed-loop"algorithm-based extraction-expert review"model is adopted to reduce data extraction errors.Expert consensus is incorporated to address decision gaps in specific clinical scenarios outlined in the guidelines,while a multi-stage,standardized output process for the AI system is established to eliminate model hallucinations.Furthermore,an evaluation framework reflecting clinical applicability is developed to enhance the AI system's accuracy and stability.Throughout the research process,it is essential to ensure the in-depth and continuous participation of multidisciplinary experts,strictly control the selection and quality evaluation of guidelines,and rely on the expert consensus method to address decision gaps in the knowledge base.Additionally,continuous validation and iterative optimization of intelligent agents are required to ensure the accuracy and stability of generated outputs.Limitations remain in the mechanisms for real-time knowledge synchronization in intelligent diagnostic and treatment systems,and further validation through large-scale real-world studies is warranted.关键词
中西医诊疗/智能体/临床实践指南/知识图谱/方法学Key words
integrated Chinese and western medicine diagnosis and treatment/intelligent agent/clinical practice guidelines/knowledge graph/methodology引用本文复制引用
周峰,陈腾飞,张婉迪,李浩源,宗星煜,林甲昊,刘清泉,赵国桢..基于临床实践指南的中西医诊疗智能体构建的方法学思考[J].中医杂志,2026,67(17):1853-1857,5.基金项目
国家自然科学基金(82505374) （82505374）
中央级公益性科研院所基本科研业务费专项资金(ZC2025011) （ZC2025011）
