眼科学报2026，Vol.41Issue(8)：669-678,10.DOI:10.12419/25082101
糖尿病患者白内障手术围手术期规范化预防用药分析
Evaluation of rational perioperative prophylactic medication uses in cataract surgery for patients with diabetes
摘要
Abstract
Objective:To assess current practices of perioperative prophylactic medication in patients with diabetes undergoing cataract surgery and to promote the standardization of perioperative prophylactic regimens.Methods:Evaluation criteria were developed based on a comprehensive literature review.Clinical data were retrieved from the Hospital Information System(HIS)for patients with diabetes undergoing cataract surgery at a designated hospital.The rationality of prophylactic medication administered preoperatively,intraoperatively,and postoperatively was systematically evaluated against the established criteria.Results:A total of 120 cases were included.Preoperatively,100%of patients received topical fluoroquinolones antibiotics,with 75.8%prescribed gatifloxacin ophthalmic gel.Irrationalities in preoperative prophylaxis primarily involved inappropriate drug combinations and incorrect dosing or administration routes.Intraoperatively,no systemic antibiotics were administered;however,34.2%of omitted povidone-iodine irrigation of conjunctival sac.Postoperatively,99.2%of patients received topical antibiotics,predominantly fluoroquinolones(82.5%),of which 71.7%were gatifloxacin ophthalmic gel.Postoperative irrationalities mainly stemmed from inappropriate combination therapy.Additionally,73.3%of patients received nonsteroidal anti-inflammatory(NSAID)eye drops,and 94.2%were prescribed topical glucocorticoids.Conclusions:Perioperative prophylactic medication for patients with diabetes undergoing cataract surgery exhibits notable deficiencies,particularly regarding irrational drug combinations and inappropriate dosing.Strengthening adherence to standardized protocols is essential.Implementing targeted evaluation criteria across the pre-,intra-,and postoperative phases can effectively guide clinical prescribing,optimize medication rationality,and enhance overall perioperative care standards.关键词
糖尿病/白内障手术/围手术期/预防性抗菌药物/合理用药Key words
diabetes mellitus/cataract surgery/perioperative period/antibiotic prophylaxis/rational drug use分类
医药卫生引用本文复制引用
陈耀升,张颖,王娟,张英杰..糖尿病患者白内障手术围手术期规范化预防用药分析[J].眼科学报,2026,41(8):669-678,10.基金项目
2025 年度郑州市医疗卫生领域科技创新指导计划项目(2025YLZDJH268).This work was supported by 2025 Zhengzhou Science and Technology Innovation Guidance Project in the Medical and Health Sector(2025YLZDJH268). （2025YLZDJH268）
