国际口腔科学杂志（英文版）2026，Vol.18Issue(4)：662-675,14.DOI:10.1038/s41368-026-00441-8
The YTHDC1-m6A-GADD45B axis promotes chondrogenesis of hPDLSCs via suppressing senescence through p53/p21 signalling pathway
The YTHDC1-m6A-GADD45B axis promotes chondrogenesis of hPDLSCs via suppressing senescence through p53/p21 signalling pathway
Dan Tan 1Qianke Tao 2Luwen Ye 3Xuemei Long 3Qiaonan Ye 4Qilin Li 3Jinlin Song 5Jingang Xiao6
作者信息
- 1. Luzhou Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China||Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences,Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education,College of Stomatology of Chongqing Medical University,Chongqing,China||Department of Periodontal and Mucosal Diseases,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China
- 2. Luzhou Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China||Department of Plastic and Burn Surgery,The Affiliated Hospital,Southwest Medical University,Luzhou,China||Department of Oral and Maxillofacial Surgery,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China
- 3. Luzhou Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China||Department of Oral Implantology,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China
- 4. Luzhou Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China||Department of Plastic and Burn Surgery,The Affiliated Hospital,Southwest Medical University,Luzhou,China
- 5. Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences,Chongqing Municipal Key Laboratory of Oral Biomedical Engineering of Higher Education,College of Stomatology of Chongqing Medical University,Chongqing,China
- 6. Luzhou Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China||Department of Plastic and Burn Surgery,The Affiliated Hospital,Southwest Medical University,Luzhou,China||Department of Oral and Maxillofacial Surgery,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China||Department of Oral Implantology,The Affiliated Stomatological Hospital,Southwest Medical University,Luzhou,China
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Dan Tan,Qianke Tao,Luwen Ye,Xuemei Long,Qiaonan Ye,Qilin Li,Jinlin Song,Jingang Xiao..The YTHDC1-m6A-GADD45B axis promotes chondrogenesis of hPDLSCs via suppressing senescence through p53/p21 signalling pathway[J].国际口腔科学杂志（英文版）,2026,18(4):662-675,14.基金项目
This work was supported by National Natural Science Foundation of China(82370938),Science&Technology Department of Sichuan Province(2024NSFSC2087),Open Project of State Key Laboratory of Oral Diseases(SKLOD2025OF05),Science and Technology Project of Health Commission of Sichuan Province(24WXXT11),Scientific and Technological Project of Luzhou(2025MYF002,2025MYF024),2023 Key Project of The Affiliated Stomatological Hospital of Southwest Medical University(2023Z02)and Stomatological Special Fund of Southwest Medical University(2024KQZX08). （82370938）
