中国畜牧杂志2026，Vol.62Issue(10)：20-27,8.DOI:10.19556/j.0258-7033.20250712-02
外源性抗氧化剂对哺乳动物卵母细胞冷冻保存的作用
The Role of Exogenous Antioxidants in the Cryopreservation of Mammalian Oocytes
摘要
Abstract
Oocyte cryopreservation holds significant value in biotechnological applications including germplasm resource preservation,in vitro embryo production,and somatic cell cloning.However,cryopreservation-induced oxidative stress impairs the developmental potential of mammalian oocytes.While endogenous antioxidant enzymes in oocytes cannot completely eliminate excessive reactive oxygen species(ROS),supplementation of exogenous antioxidants in cryopreservation media have been employed to reduce oxidative damage.This review comprehensively examines the various forms of oxidative stress induced by cryopreservation in mammalian oocytes,with particular focus on elucidating the regulatory mechanisms of both non-enzymatic and enzymatic antioxidant defense systems.Moreover,we critically evaluate the efficacy and underlying mechanisms of diverse antioxidants in counteracting oxidative damage,thereby providing valuable references for enhancing the efficiency of mammalian oocyte cryopreservation.关键词
哺乳动物/卵母细胞/冷冻保存/氧化应激/抗氧化剂Key words
Mammalian/Oocyte/Cryopreservation/Oxidative stress/Antioxidant分类
农业科技引用本文复制引用
翟登荣,李晓霞..外源性抗氧化剂对哺乳动物卵母细胞冷冻保存的作用[J].中国畜牧杂志,2026,62(10):20-27,8.基金项目
吉林省科技发展计划项目(20240303071NC) （20240303071NC）
