中国畜牧杂志2026，Vol.62Issue(10)：59-65,7.DOI:10.19556/j.0258-7033.20250924-01
免疫细胞在畜禽脂肪产热中的调控作用
Regulatory Role of Immune Cells in Thermogenesis of Livestock and Poultry Adipose Tissue
摘要
Abstract
Adipose tissue is a vital metabolic organ that functions in both energy storage and thermogenesis.Brown and beige adipocytes serve as key thermogenic cells,whose differentiation and thermogenic activity are regulated by various factors.Immune cells play a central role in this process through the secretion of cytokines,with macrophages and ILC2s occupying pivotal positions in the regulatory network.Furthermore,cells such as ILC2s,Th2 cells,Tregs,iNKT cells,and γδ T cells participate through diverse mechanisms,collectively forming an immune-metabolic regulatory network that maintains systemic energy homeostasis.While current researches in this field are largely based on mouse models,studies on the underlying mechanisms in livestock remain limited.Nevertheless,thermogenic capacity not only influences environmental adaptation in animals but is also closely associated with key production traits such as disease resistance,feed efficiency,and body fat deposition.Therefore,this review summarizes recent advances in the mechanisms by which immune cells regulate adipose thermogenesis,along with preliminary findings in livestock,with the aim of highlighting the potential of this research direction to inform the development of novel green feed additives,improve cold resistance and meat quality in livestock,and thereby promote the sustainable development of green animal husbandry.关键词
脂肪组织/棕色脂肪组织/米色化/产热/免疫细胞Key words
Adipose tissue/Brown adipose tissue/Beiging/Thermogenesis/Immune Cells分类
农业科技引用本文复制引用
马红,汪亮,付博,王芳,郭镇华,刘娣..免疫细胞在畜禽脂肪产热中的调控作用[J].中国畜牧杂志,2026,62(10):59-65,7.基金项目
国家自然科学基金(32630099) （32630099）
黑龙江省科研业务费(CZKYF2023-1-B009) （CZKYF2023-1-B009）
