中国医学创新2026，Vol.23Issue(25)：47-52,6.DOI:10.3969/j.issn.1674-4985.2026.25.010
AVAPS无创呼吸模式治疗危重症急性呼吸衰竭患者的有效性研究
Study on the Effectiveness of AVAPS Non-invasive Ventilation Mode in the Treatment of Critically Ill Patients with Acute Respiratory Failure
摘要
Abstract
Objective:To investigate the clinical effect of average volume assured pressure support(AVAPS)non-invasive ventilation mode in critically ill patients with acute respiratory failure.Method:Eighty-six critically ill patients with acute respiratory failure who received non-invasive ventilation in the Department of Critical Care Medicine,Shangrao People's Hospital from January to October 2025 were selected and divided into two groups by random number table method,with 43 cases in each group.The control group received conventional non-invasive ventilation[autonomous/timed(S/T)mode],and the observation group received AVAPS non-invasive ventilation mode.Arterial blood gas indexes[pH value,PaCO2,PaO2/fraction of inspired oxygen(FiO2)]before ventilation and after 4,8,12,24,48 and 72 hours of ventilation,vital signs(systolic blood pressure,diastolic blood pressure,heart rate)before ventilation and after 72 hours of ventilation,respiratory mechanics parameters[tidal volume(VT),minute resting ventilation(VE),respiratory rate(RR)]within 7 days of ventilation,and clinical outcomes were compared between the two groups.Result:After 48 and 72 hours of ventilation,the pH value of the observation group were significantly higher than those of the control group(P<0.05).After 8,12 and 72 hours of ventilation,PaCO2 in the observation group were significantly lower than those in the control group(P<0.05).After 24,48,and 72 hours of ventilation,the PaO2/FiO2 in the observation group were significantly higher than those in the control group(P<0.05).After 72 hours of ventilation,the systolic blood pressure,diastolic blood pressure and heart rate in both groups were lower than those before ventilation,and those of the observation group were lower than those of the control group(P<0.05).Within 7 days of ventilation,VT and VE in the observation group were higher than those in the control group,and RR was lower than that in the control group(P<0.05).The tracheal intubation rate and the mortality rate during hospitalization in the observation group were lower than those in the control group,but the differences were not statistically significant(P>0.05).The hospitalization time of the observation group was shorter than that of the control group(P<0.05).Conclusion:AVAPS non-invasive ventilation mode can more rapidly and effectively improve arterial blood gas,respiratory mechanics indexes and vital signs,shorten hospital stay.关键词
平均容量保证压力支持无创呼吸模式/急性呼吸衰竭/无创通气/动脉血气/呼吸力学/临床转归Key words
Average volume assured pressure support non-invasive ventilation mode/Acute respiratory failure/Non-invasive ventilation/Arterial blood gas/Respiratory mechanics/Clinical outcome分类
医药卫生引用本文复制引用
王飞,王敢,汪嘉伟,娄文水..AVAPS无创呼吸模式治疗危重症急性呼吸衰竭患者的有效性研究[J].中国医学创新,2026,23(25):47-52,6.基金项目
上饶市科技计划指导性项目(20242CZDX30) （20242CZDX30）
