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- Editor-in-Chief:Chuan QinCSCD摘要：Chuan Qin,MD,PhD,is the President of the Chinese Associaon for Laboratory Animal Sciences(CALAS),and the permanent professor of Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC).Moreover…查看全部>>
- Anti-apoptotic protein BCL-XL as a therapeutic vulnerability in gastric cancer北大核心CSCD摘要：Background: New therapeutic targets are needed to improve the outcomes for gastric cancer(GC) patients with advanced disease. Evasion of programmed cell death(apoptosis) is a hallmark of cancer cells and direct inductio…查看全部>>
- Humanization for neurological disease modeling:A roadmap to increase the potential of Drosophila model systems北大核心CSCD摘要：Neuroscience and neurology research is dominated by experimentation with rodents.Around 75%of neurology disease-associated genes have orthologs in Drosophila mel-anogaster,the fruit fly amenable to complex neurolo…查看全部>>
- Whole mount of adult ear skin as a model to study vascular malformationsCSCD摘要：Background:Genetic analysis in human patients has linked mutations in PIK3CA,the catalytic subunit of PI-3′Kinase,to sporadic incidences of vascular malformations.Methods:We have developed a mouse model with inducible a…查看全部>>
- Natural products and extracts from plants as natural UV filters for sunscreens:A review北大核心CSCD摘要：Although solar exposure is necessary for human health,phototoxicology induced by excessive UVB and UVA radiation,which involves sunburns,skin aging and even tu-morigenesis,has been widely researched.Sunscreen is one of …查看全部>>
- A combined pig model to determine the net absorption of volatile fatty acids in the large intestine under different levels of crude fiberCSCD摘要：Background:This study aimed to develop a combined model to quantify the net absorption of volatile fatty acids(VFA)in the large intestine(LI)of pigs.Methods:Fifteen female growing pigs(Duroc×Large White×Landrace)were ra…查看全部>>
- A novel pulmonary fibrosis murine model with immune-related liver injury北大核心CSCD摘要：Idiopathic pulmonary fibrosis(IPF),characterized by aggravated alveolar destruc-tion and fibrotic matrix deposition,tendentiously experiences the stage called acute exacerbation IPF(AE-IPF)and progresses to multip…查看全部>>
- Lowering fasting blood glucose with non-dialyzable material of cranberry extract is dependent on host genetic background,sex and diet北大核心CSCDchow diet(CHD)collaborative cross(CC)mouse modelfasting blood glucose(FBG)high-fat diet(HFD)non-dialyzable material(NDM)of cranberry extracttype 2 diabetes(T2D)摘要：Background:Type 2 diabetes(T2D)is a polygenic metabolic disease,character-ized by high fasting blood glucose(FBG).The ability of cranberry(CRN)fruit to regulate glycemia in T2D patients is well known.Here,a cohort of 13…查看全部>>
- Biology and function of pericytes in the vascular microcirculationCSCD摘要：Pericytes are the main cellular components of tiny arteries and capillaries.Studies have found that pericytes can undergo morphological contraction or relaxation under stimulation by cytokines,thus affecting the contrac…查看全部>>
- Development of radiation countermeasure agents for acute radiation syndromesCSCDChinese herbal medicinesessential medicines listionizing radiationradiation countermeasure agentsradiation injury摘要：The risk of internal and external exposure to ionizing radiation(IR)has increased alongside the development and implementation of nuclear technology.Therefore,serious security issues have emerged globally,and there has …查看全部>>