食品与发酵工业2009，Vol.35Issue(6)：1-5,5.
超高倍甜味剂N-[3-(3-羟基-4-甲氧基苯基)丙基]-阿斯巴甜的合成研究
Synthesis of High Potency Sweetener N-[3-(3-hydroxy-4-methoxyphenyl) propyl]-aspartyl-L-henylalaninel-methylester
摘要
Abstract
The development of high potency sweetener changes rapidly, sweetener with safety, low cost, high de-gree of sweetness and top properties is the trend in food industry. On the basis of sweet mechanism, by the reaction of aspartame and 3-hydroxy-4-methoxyphenylpropylaldehyde under the catalysis Pd/C, a new sweetener N-[3-(3-hy-droxy-4-methoxyphenyl) propyl]-aspartyl-L-henylalaninel-methylester is synthesized. Because of hydrophobic group added on aspartame derivative, the sweetness is 23 000 times higher than that of cane sugar. Furthermore, the method is simple and available with high yield. The paper summarizes the synthesis method of the important intermediate, 3-hydroxy-4-methoxyphenylpropylaldehyde, with 49.8% yield, which makes the high potency sweetener possible.关键词
3-羟基-4-甲氧基苯丙醛/N-[3-(3-羟基-4-甲氧基苯基)丙基]-阿斯巴甜/疏水基团/甜度Key words
3-hydroxy-4-methoxyphenylpropylaldehyde, N-[3-(3-hydroxy-4-methoxyphenyl)propyl]-aspartyl-L-he-nylalaninel-methylester, hydrophohic group, sweetness分类
轻工纺织引用本文复制引用
吴美红,郑建仙..超高倍甜味剂N-[3-(3-羟基-4-甲氧基苯基)丙基]-阿斯巴甜的合成研究[J].食品与发酵工业,2009,35(6):1-5,5.基金项目
国家自然科学基金资助项目(20576044) （20576044）
