食品科学2006，Vol.27Issue(6)：203-206,4.
大豆皂甙对肝癌H22小鼠的抗肿瘤研究
Study on Antitumor Inhibition of Soyasaponins on Hepatocarcinoma H22 Mice
肖军霞 1朱彩平 1任丹丹 1黄红霞 1张声华1
作者信息
- 1. 华中农业大学食品科技学院,湖北,武汉,430070
- 折叠
摘要
Abstract
Using hepatocarcinoma H22 tumor-bearing mice as model, the inhibifion effect of soyasaponin fraction (SS Ⅱ) onhepatocarcinoma H22 mice was observed at dosages of 10, 20 and 30mg/kg/day by systematically studying the H22 tumor inhibitionrate, cellular immunity and antioxidant level. In this study, SS Ⅱ inhibited the growth of transplanted hepatocarcinoma H22,increased the DTH response, promoted the proliferation of T lymphocyte and NK cell activity significantly, improved thesuperoxide dismutase (SOD) activity and decreased the malondialdehyde (MDA) content significantly. The mechanism of SS Ⅱabout antitumor inhibition might be the enhancing of the cellular immune function and the improving of the antioxidant capabilityin H22 tumor-bearing mice.关键词
大豆皂甙SSⅡ/肝癌H22/细胞免疫/抗氧化Key words
soyasaponins SS Ⅱ/hepatocarcinoma H22/cellular immunity/antioxidant分类
轻工纺织引用本文复制引用
肖军霞,朱彩平,任丹丹,黄红霞,张声华..大豆皂甙对肝癌H22小鼠的抗肿瘤研究[J].食品科学,2006,27(6):203-206,4.
