食品与机械2009，Vol.25Issue(4)：56-59,4.
杜仲雄花正丁醇提取物的镇静催眠作用研究
Study on the sedative and hypnotic effects of n-butyl alcohol extracts of eucommia male flowers
摘要
Abstract
Study the sedative and hypnotic effects of n-butyl alcohol extracts of Eucommia male flowers with different dose. Confirm the effective part of Eucommia male flowers and investigate the effective dosage of it. Extract active components in Eucommia male flowers with the n-butyl alcohol. We investigated the effects on spontaneous activity of mice, the synergy operation with pentobarbital sodium, and anticonvulsant effects of n-butyl alcohol extracts of Eucommia male flowers with different dose. N-butyl alcohol extracts of Eucommia male flowers could induce mice to sleep or significantly inhibit the spontaneous activity, enhance the amount of sleeping mice with pentobarbital sodium of subthreshold dose, prolong the sleeping time and shorten the sleep latency of pentobarbital sodium of superthreshold dose; effectively reduce the eclamptic rate of mice and significantly prolonged the convulsions latency. N-butyl alcohol extracts of Eucommia male flowers possess obviously sedative and hypnotic effects in mice which are the effective part of Eueommia male flowers.关键词
杜仲雄花/正丁醇提取物/镇静/催眠Key words
Eucommia male flowers/N-butyl alcohol extracts/Sedation, Hypnosis分类
轻工纺织引用本文复制引用
李欣,樊金铃,朱文学,马海乐,刘少阳..杜仲雄花正丁醇提取物的镇静催眠作用研究[J].食品与机械,2009,25(4):56-59,4.基金项目
河南省教育厅自然科学基金资助项目(编号:2006550001) （编号:2006550001）
