食品与发酵工业2011，Vol.37Issue(4)：97-101,5.
芭蕉芋糖浆发酵生产丁二酸培养基的优化
Optimization of Fermentation Medium for Succinic Acid Production Using Canna edulis ker Syrup
摘要
Abstract
Canna edulis Ker syrup was firstly used to product succinic acid by Actinobacillus succinogenes CGMCC1593. It was found that the total sugar, corn steep liquid and phosphate significantly improved the production of succinic acid. The Response Surface Methodology (RSM) based on a three-factor Box-Behnken design of experiments was used to build an analytical model and finally employed as a constraint in an obvious optimization process. The optimized parameters were total sugar of 89.66 g/L, corn steep liquid of 38.55 g/L, and phosphate of 4.46 g/L. Under those optimization conditions, it was predicted that the the highest concentation of succinic acid recached 62.92 g/L.After optimization, the succinic acid production increased by 22. 7％ , and the experimental data basically in line with the predicted values.关键词
丁二酸/芭蕉芋/响应面分析法Key words
succinic acid/ Canna edulis Kef/ response surface methodology引用本文复制引用
刘宇鹏,陈万河,陈梁,方晨,白彦兵,孙志浩..芭蕉芋糖浆发酵生产丁二酸培养基的优化[J].食品与发酵工业,2011,37(4):97-101,5.基金项目
浙江杭州鑫富药业公司博士后科研基金资助 （）
