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紫甘薯叶总黄酮对四氯化碳致小鼠慢性肝损伤的保护作用

吕晓玲 陶东川 马天娇 刘迎旺 温娟 张新伟

食品工业科技2011,Vol.32Issue(6):371-372,375,3.
食品工业科技2011,Vol.32Issue(6):371-372,375,3.

紫甘薯叶总黄酮对四氯化碳致小鼠慢性肝损伤的保护作用

Protective effect of total flavonoids of purple sweet potato leaves on carbon tetrachloride-induced chronic liver injury in mice

吕晓玲 1陶东川 1马天娇 1刘迎旺 1温娟 1张新伟1

作者信息

  • 1. 天津科技大学食品工程与生物技术学院,天津300457
  • 折叠

摘要

Abstract

The protective effect of total flavonoids of purple sweet potato leaves (FPSPL)on carbon tetrachlorideinduced chronic liver injury in mice was studied. The chronic liver injury model was induced by administration of 7%carbon tetrachloride and mice were treated of FPSPL at 50,100 or 200mg/kg to examine the changes of liver index (LI) ,alanine aminotrasferase(ALT) ,aspartate aminotrasferase(AST) ,albumin(ALB) ,total protein(TP)in serum,superoxide dismutase (SOD)and malondialdehyde (MDA)in liver homogenate. The results showed that FPSPL significantly decreased LI, the activity of serum ALT and AST, the level of MDA in liver homogenate. It also increased the concentration of serum ALB and TP,the activity of SOD in liver homogenate. FPSPL had protective effect on mice with chronic liver injury induced by carbon tetrachloride.

关键词

紫甘薯叶总黄酮/CCl4/慢性肝损伤

Key words

FPSPL/ CCl4/ chronic liver injury

分类

轻工纺织

引用本文复制引用

吕晓玲,陶东川,马天娇,刘迎旺,温娟,张新伟..紫甘薯叶总黄酮对四氯化碳致小鼠慢性肝损伤的保护作用[J].食品工业科技,2011,32(6):371-372,375,3.

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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