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苹果提取物对小鼠脂肪代谢的影响

周丽萍 王振宇 刘瑜

食品工业科技2011,Vol.32Issue(6):380-383,4.
食品工业科技2011,Vol.32Issue(6):380-383,4.

苹果提取物对小鼠脂肪代谢的影响

Effect of apple extracts on mice lipid metabolism

周丽萍 1王振宇 2刘瑜3

作者信息

  • 1. 黑龙江省科学院自然与生态研究所,黑龙江哈尔滨150040
  • 2. 东北林业大学林学院,黑龙江哈尔滨150040
  • 3. 哈尔滨工业大学食品科学与工程学院,黑龙江哈尔滨150001
  • 折叠

摘要

Abstract

Objective :To study the effect of apple extracts on lipid metabolism in mice. Method :60 mice were divided into 5 groups randomly. Except normal control group, the other four groups were fed high fat diet. Normal control and obesity control groups were fed i.g. normal saline,the other three groups were fed i.g.38,76 and 114g/kg · bw apple extracts. The mice were killed after 4 weeks,the mice body weight,the content of serum total triglycerides (TG) ,total cholesterol(TC), high density lipoprotein cholesterol(HDL-C) ,malondialdehyde(MDA) ,the activity of superoxide dismutase( SOD), glutathione peroxidase( GSH- PX), hepatic lipase(HL) and lipoprotein lipase(LPL) were assayed. Results:Apple extracts could obviously reduce the mice body weight,the content of TG,TC, low density lipoprotein cholesterol ( LDL- C) and MDA, and atherosclerosisdisease index ( Al ). It could also improve HDL-C and the activity of SOD, GSH-PX, HL and LPL in their blood serum. Conclusion:The apple extracts have the functions in reducing blood lipid by adjusting the lipid metabolism of mice.

关键词

苹果提取物/血脂/脂质过氧化/脂肪代谢

Key words

apple extracts/ blood lipid /lipid peroxidation /lipid metabolism

分类

轻工纺织

引用本文复制引用

周丽萍,王振宇,刘瑜..苹果提取物对小鼠脂肪代谢的影响[J].食品工业科技,2011,32(6):380-383,4.

基金项目

东北林业大学研究生创新项目. ()

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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