现代食品科技2011,Vol.27Issue(4):376-379,4.
黄芪多糖的分离纯化和抗肿瘤活性研究
Extraction and Purification of Astragalus Polysaccharide and its Anti-tumor Activity
摘要
Abstract
Different factors and levels were used for the Astragalus polysaccharide extraction by water bath. The results showed that the best ratio of solid to liquid, extraction temperate and time were in 1∶10, 80 ℃ and 2 h, respectively, under which the extraction rate could reach 9.77% under such conditions. Two types of Astragalus polysaccharide were obtained after alcohol precipitate and purification of DEAE-Sephadex A-25 and Sephadex G-100. The result of anti-tumor activity research showed that at dose of 50 mg/kg, 100 mg/kg, the inhibitory rates of two kinds of polysaccharide were 49.81%, 55.47%, 45.46% and 47.72%.关键词
黄芪多糖/提取/纯化/抗肿瘤Key words
Astragalus polysaccharide/ extraction/ purification/ anti-tumor引用本文复制引用
朱振元,刘荣强,周芳,李盛峰,原静..黄芪多糖的分离纯化和抗肿瘤活性研究 [J].现代食品科技,2011,27(4):376-379,4.基金项目
天津市科技计划项目应用基础与前沿技术研究计划重点项目(09JCZDJC21800)、天津市高等学校科技发展基金计划项目(20090604) (09JCZDJC21800)