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Epithelial-mesenchymal transition in breast cancer progression and metastasisOACSCDCSTPCD

Epithelial-mesenchymal transition in breast cancer progression and metastasis

英文摘要

Breast cancer is the most common cancer in women,and approximately 90% of breast cancer deaths are caused by local invasion and distant metastasis of tumor cells.Epithelial-mesenchymal transition (EMT) is a vital process for large-scale cell movement during morphogenesis at the time of embryonic development.Tumor cells usurp this developmental program to execute the multi-step process of tumorigenesis and metastasis.Several transcription factors and signals …查看全部>>

Yifan Wang;Binhua P. Zhou

Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40506, USAMarkey Cancer Center, University of Kentucky College of Medicine, Lexington, KY 40506, USA

Breast cancer epithelial-mesenchymal transition metastasis signaling pathway Snail

Breast cancer epithelial-mesenchymal transition metastasis signaling pathway Snail

《癌症(英文版)》 2011 (9)

603-611,9

the grants from NIH (RO1CA125454),the Susan G.Komen Foundation (KG081310),and the Mary Kay Ash Foundation (to B.P,Zhou).

10.5732/cjc.011.10226

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