食品工业科技Issue(8)：336-339,4.
N-[N-3-（3-羟基-4-甲氧基苯基）丙基-L-α-天冬氨酸]-L-苯丙氨酸-1-甲酯的合成研究
Synthesis of N-[N-3-（3-Hydroxy-4-Methoxyphenyl） Propyl-L-α-Aspartate]-L-Phenylalanine-1-Methyl
摘要
Abstract
N-[N-3-（3-Hydroxy-4-Methoxyphenyl）Propyl-L-α-Aspartate]-L-Phenylalanine-1-Methyl,a neotame analogue sweeteners with the sweetness 20000 times higher than sucrose,was synthesized with production yield of 32% under the following condition.Using 3-hydroxy-4-methoxybenzaldehyde and acetaldehyde as original material,made them reacting at-10℃ and strong alkaline condition and N-[N-3-（3-Hydroxy-4-Methoxyphenyl）Propyl-L-α-Aspartate]-L-Phenylalanine-1-Methyl was formed.And then reacted with aspartame（APM）at 35℃ and under hydrogen pressure of 0.7MPa in the presence of 10%Pd/C catalyst for alkylation to produce the final product.关键词
3-羟基-4-甲氧基苯甲醛/3-羟基-4-甲氧基肉桂醛/阿斯巴甜/纽甜类似物Key words
3-hydroxy-4-methoxybenzaldehyde/3-hydroxy-4-methoxycinnamylaldehyde/asparty/neotame analogue分类
轻工纺织引用本文复制引用
甘水锋,晏日安,李爱军..N-[N-3-（3-羟基-4-甲氧基苯基）丙基-L-α-天冬氨酸]-L-苯丙氨酸-1-甲酯的合成研究[J].食品工业科技,2011,(8):336-339,4.基金项目
广东高校科技成果转化项目 （）
广东省重大科技专项 （）
