首页|期刊导航|中国神经再生研究(英文版)|Expression of nerve growth factor precursor, mature nerve growth factor and their receptors during cerebral ischemia-reperfusion injury

Expression of nerve growth factor precursor, mature nerve growth factor and their receptors during cerebral ischemia-reperfusion injuryOACSCD

Expression of nerve growth factor precursor, mature nerve growth factor and their receptors during cerebral ischemia-reperfusion injury

英文摘要

We investigated nerve growth factor precursor (proNGF) and mature NGF expression in ischemic and non-ischemic cortices after cerebral ischemia-reperfusion injury.In both ischemic and non-ischemic cortices, proNGF was found to be present in the extracellular space and cytoplasm.In addition, mature NGF was expressed in extracellular space, but with a very low signal.In ischemic cortex only, proNGF was significantly decreased, reaching a minimal level at 1 day.…查看全部>>

Guoqian He;Jian Guo;Jiachuan Duan;Wenming Xu;Ning Chen;Hongxia Li;Li He

Department of Neurology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, ChinaDepartment of Neurology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, ChinaNational Chengdu Center for Safety Evaluation of Traditional Chinese Medicine, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, ChinaJoint Laboratory of Reproductive Medicine, Sichuan University-The Chinese University of Hongkong Joint Laboratory for Reproductive Medicine (SCU-CUHK), Institute of Women and Children's Health, Department of Obstetrics and Gynecology, West China Second UnDepartment of Neurology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, ChinaNational Chengdu Center for Safety Evaluation of Traditional Chinese Medicine, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, ChinaDepartment of Neurology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China

cerebral ischemia-reperfusion injurynerve growth factor precursormature nerve growth factorp75 neurotrophin receptorcell apoptosis

cerebral ischemia-reperfusion injurynerve growth factor precursormature nerve growth factorp75 neurotrophin receptorcell apoptosis

《中国神经再生研究(英文版)》 2011 (22)

1701-1708,8

the National High Technology Program of China (863 Programs),No.2006AA02A117

10.3969/j.issn.1673-5374.2011.22.004

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