均匀设计法优选胡黄连中胡黄连苷的提取工艺OACSCDCSTPCD
Optimization of the Extraction Technology of Picroside from Picrorhiza scrophulariiflora with Uniform Design Method
目的:优选胡黄连中有效成分胡黄连苷I、Ⅱ的最佳提取工艺.方法:选用均匀设计试验,以胡黄连苷I、Ⅱ的总转移率为指标,考察乙醇浓度、提取时间、提取次数及乙醇用量对胡黄连苷I、Ⅱ提取的影响.结果:最佳提取工艺为胡黄连饮片加65%乙醇10倍量,提取3次,每次2h.结论:所优化的工艺可靠,适用于胡黄连中胡黄连苷I、Ⅱ的提取.
OBJECTIVE: To optimize the extraction technology of picroside I and picroside II from Picrorhiza scrophulariiflora by uniform design method. METHODS: Taking total transfer rate of picroside I and picroside D as index, the effects of the concentration of alcohol, solvent amount, extraction time and extraction frequency on extraction technology were evaluated by uniform design method. RESULTS: The optimal technology was as follows: 10-fold 65% alcohol, extract…查看全部>>
段晓颖;高卫芳;吴彩丽;张辉
河南中医学院第一附属医院国家中医药管理局中药制剂三级实验室,郑州市450000河南新乡医学院第一附属医院,卫辉市453100河南中医学院第一附属医院国家中医药管理局中药制剂三级实验室,郑州市450000河南中医学院第一附属医院国家中医药管理局中药制剂三级实验室,郑州市450000
医药卫生
胡黄连胡黄连苷I胡黄连苷Ⅱ均匀设计提取工艺
Picrorhiza scrophulariiflora Picroside I Picroside II Uniform design Extraction technique
《中国药房》 2011 (39)
3675-3676,2
河南省科技发展计划项目(072102330035)
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