茶叶科学2011，Vol.31Issue(5)：405-410,6.
茶多酚抗辐射制剂安全毒理学研究
Study on the Toxicology of an Anti-radiation Preparation of Tea-polyphenols
摘要
Abstract
To evaluate the edible safety of anti-radiation preparations of tea polyphenol, the experiment included acute toxicity test, Ames test, micronucleus test, sperm shape abnormality test and thirty days feeding test were performed. Results showed that the oral maximum tolerance dose(MTD) was higher than 20.0 g/kgbw both in female and male mice and rats. The results on toxicity of Ames test, micronucleus test, sperm shape abnormality test and mutagencity were negative. No toxicological symptom was appeared in tested animals from thirty days feeding test. It is concluded that the anti-radiation preparations of tea-polyphenol was classified as non-toxicology and genotoxicity, high edible safety.关键词
茶多酚抗辐射制剂/急性毒性/最大耐受量/遗传毒性/安全性Key words
anti-radiation preparations of tea-polyphenols, acute toxicity, maximum tolerated dose, genotoxicity,edible safety分类
农业科技引用本文复制引用
王岳飞,梁善珠,张士康,陈红波,朱跃进,黄爽如,杨贤强..茶多酚抗辐射制剂安全毒理学研究[J].茶叶科学,2011,31(5):405-410,6.基金项目
浙江省人事厅留学回国基金J20090040 （）
