食品工业科技Issue(11)：168-170,173,4.
梅花总黄酮对黄嘌呤氧化酶的抑制作用及其抗氧化活性评价
Inhibitory effect on xanthine oxidase and antioxidant activity of total flavonoids from Prunus mume flowers
郑小微 1夏道宗 2张英1
作者信息
- 1. 浙江大学生物系统工程与食品科学学院,浙江杭州310029
- 2. 浙江中医药大学药学院,浙江杭州310053
- 折叠
摘要
Abstract
The inhibitory effect on xanthine oxidase（XOD）and antioxidant activities of total flavonoids from Prunus mume flowers（PMF）were studied.The inhibitory effect of PMF on XOD was determined in vitro.DPPH free radical method,ferric ion reducing power method and total antioxidant capacity in blood（T-AOC）assays were individually used here to evaluate the antioxidant activity of PMF.The result showed that the inhibitory effect of PMF on XOD was a dosage-dependent manner with IC50value at 85.45μg/mL.PMF＇s scavenging capacity on DPPH free radical was stronger than bamboo leaf flavonoids（BLF）,and weaker than VC and rutin.PMF＇s reducing ability on ferric ion was 1.44 fold and 1.29 fold stronger than that of rutin and BLF.And the consequence of total antioxidant power in blood was as follows：VCPMFBLFrutin.This study elucidated that the total flavonoids from Prunus mume flowers was an outstanding bio-antioxidant and XOD inhibitor.It was of potential value used as a dietary supplement preventing from oxidation stress and hyperuricemia.关键词
青梅/梅花总黄酮/黄嘌呤氧化酶/抑制作用/抗氧化活性Key words
Prunus mume/total flavonoids from Prunus mume flowers/xanthine oxidase/inhibitory effect/antioxidant activity分类
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郑小微,夏道宗,张英..梅花总黄酮对黄嘌呤氧化酶的抑制作用及其抗氧化活性评价[J].食品工业科技,2011,(11):168-170,173,4.
