食品工业科技Issue(1)：379-381,3.
天然虾青素对辐射损伤小鼠辅助保护作用
Assisting protective effect of natural astaxanthin against irradiation injury in mice
陈东方 1王海玉 1李立 1张聪恪 1徐冰 1刘翠娥1
作者信息
- 1. 河南省疾病预防控制中心,河南郑州450016
- 折叠
摘要
Abstract
Objective：To explore the protective effects of natural astaxanthin against irradiation injury in mice.Methods：144 mice were divided into irradiating control group and three experiment groups,treated with natural astaxanthin 100,200,600mg/kg·bw respectively for 20 days.All animals were irradiated by 60Co γ-ray and continued to be orally administered.The number of white blood cells was counted before irradiating,on the 3rd and 14th day after irradiating.The number of karyota of femur and the frequency of micronuclei in polychromatophilic erythrocytes（PCE） of bone marrow in mice were measured on the 3rd day after irradiating.The level of hemolysin was measured on the 14th day after irradiating.Results：Compared with the irradiating control group,the number of WBC and the level of hemolysin in the group of 600mg/kg·bw were increased significantly（P0.05）,while karyota of femur and the frequency of micronuclei in PCE of bone marrow in the groups of 200mg/kg·bw and 600mg/kg·bw were decreased significantly（P0.05）.Conclusion：Natural astaxanthin could protect mice from irradiation injury.关键词
天然虾青素/辐射损伤/保护作用/小鼠Key words
natural astaxanthin/irradiation injury/protect effect/mice分类
轻工纺织引用本文复制引用
陈东方,王海玉,李立,张聪恪,徐冰,刘翠娥..天然虾青素对辐射损伤小鼠辅助保护作用[J].食品工业科技,2012,(1):379-381,3.
